Rifampin and tobramycin combination with PMMA antibiotic cement

European Journal of Orthopaedic Surgery & Traumatology : Orthopédie Traumatologie
Elive F Likine, David Seligson

Abstract

Rifampin is a powerful antibiotic used in the treatment of biofilm-forming bacteria with studies supporting its use in PMMA cement. However, it has not been widely accepted for its use in PMMA cement due to a perception that it is unable to solidify in a timely manner. The technique described consists of ratio of aminoglycoside and rifampin that reduces time to solidification to approximately 15-20 min.

References

Aug 19, 2004·Orthopedics·Sudhakar G MadanagopalCraig S Roberts
Apr 24, 2013·World Journal of Orthopedics·Manit AroraAshish D Diwan
Apr 22, 2015·Clinical Orthopaedics and Related Research·Carlos J SanchezJoseph C Wenke
Jan 3, 2016·Biomaterials·Jason A InzanaHani A Awad

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