RIG-I works double duty

Cell Host & Microbe
Ying Kai Chan, Michaela U Gack

Abstract

The pathogen sensor RIG-I recognizes viral RNA and signals to induce an antiviral response. In this issue of Cell Host & Microbe, Weber et al. (2015), along with recent work by Sato et al. (2015), demonstrate that RIG-I directly inhibits viral replication independent of antiviral signaling.

References

Oct 14, 2006·Science·Andreas PichlmairCaetano Reis e Sousa
Feb 17, 2009·Lancet·Yun-Fan Liaw, Chia-Ming Chu

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Citations

Jul 15, 2015·Cytokine·Friedemann Weber
Oct 30, 2016·Current Opinion in Immunology·Michaela Weber-Gerlach, Friedemann Weber

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