Right atrial thrombosis complicating renal transplantation in a child

Pediatric Transplantation
Yelda BilginerAysin Bakkaloglu

Abstract

Nephrotic syndrome represents a form of acquired thrombophilia thereby causing increased risk of thrombosis. In patients with nephrotic syndrome both venous and arterial thrombosis can occur; however, intracardiac thrombus is among the rarest reported in the literature. In this case report, we present a 10.5-yr-old boy with right atrial thrombosis and an acute rejection episode after renal transplantation due to end stage renal disease caused by focal segmental glomerulosclerosis manifested by nephrotic syndrome. The clinical course was successfully managed with surgical removal of thrombus, institution of anticoagulant as well as antirejection therapy. This report draws attention to the risks that could be associated with thrombosis in renal recipients with congenital or acquired thrombophilias and emphasizes the importance of identifying risk factors for thrombosis in these patients.

References

Jan 1, 1996·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·F KronenbergH Dieplinger
Apr 29, 1998·The New England Journal of Medicine·S R Orth, E Ritz
May 16, 1998·Transplantation·M FischerederW Land
Sep 19, 1998·The New England Journal of Medicine·H W Daniell
Oct 7, 2000·Stroke; a Journal of Cerebral Circulation·G GüntherUNKNOWN Childhood Stroke Study Group
Apr 17, 2002·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Wanja WeiszDirk E Müller-Wiefel
Dec 31, 2002·Journal of the American Society of Nephrology : JASN·Stefan HeidenreichUlrike Nowak-Göttl
Dec 3, 2003·The New England Journal of Medicine·Abraham A AriyoUNKNOWN Cardiovascular Health Study Investigators
Aug 3, 2005·Pediatrics·John Kylan LynchKarin B Nelson
Oct 6, 2006·Journal of the National Comprehensive Cancer Network : JNCCN·Michael L Linenberger
Oct 13, 2006·Pediatric Transplantation·Birgitta KranzPeter F Hoyer
Mar 17, 2007·Hematology·Marco Zaffanello, Massimo Franchini
Aug 7, 2007·The American Journal of Medicine·Francesco SofiDomenico Prisco

❮ Previous
Next ❯

Citations

Mar 1, 2012·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Fatemeh Ghane SharbafJohn-Paul Capolicchio
Jul 6, 2014·Clinical and Experimental Nephrology·Betul TavilFatma Gumruk
Mar 23, 2010·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Janet Yk YangAnthony Kc Chan

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.