Right ventricular diastolic dysfunction in heart failure

Circulation
C M YuK S Woo

Abstract

Left ventricular (LV) diastolic dysfunction is common in heart failure and is an important predictor of prognosis and mortality. Less attention has been paid to right ventricular (RV) diastolic function. In this study, we compared RV diastolic function in a large cohort of patients with heart failure (HF) with two groups: patients with pulmonary hypertension and normal LV function (the PHT group) and normal subjects. Transtricuspid and pulmonary artery flow were assessed by two-dimensional Doppler echocardiography at maximum inspiration and expiration in 185 subjects: 114 symptomatic HF patients (ejection fraction < 0.5), 31 PHT patients (pulmonary artery systolic pressure > 40 mm Hg), and 40 normal subjects. A subset was matched for age and heart rate. The results showed a high prevalence of RV diastolic abnormalities: HF patients had lower tricuspid E-A ratios, lower peak E-wave velocity, and prolonged RV isovolumic relaxation time (all P< .0001). Tricuspid E-wave deceleration time was significantly shorter only in those who had an LV restrictive filling pattern. The PHT group had similar findings. Compared with a normal range, more than half of the patients had lower tricuspid E-A ratios (HF, 55%; PHT, 69%), and 61% of HF an...Continue Reading

References

Sep 1, 1976·Journal of Applied Physiology·W P SantamoreA A Bove
Oct 1, 1991·Current Problems in Cardiology·L J Dell'Italia
Feb 1, 1989·European Heart Journal·C UiterwaalO Daniels
Sep 11, 1967·The American Journal of Physiology·R R TaylorJ Ross
Apr 1, 1995·Journal of the American College of Cardiology·T G Di SalvoG W Dec
Jul 1, 1994·Journal of the American College of Cardiology·G Y XieA N DeMaria
Jan 1, 1994·Progress in Cardiovascular Diseases·R A Nishimura, A J Tajik

❮ Previous
Next ❯

Citations

Sep 1, 2009·Annals of Biomedical Engineering·Joost LumensTheo Arts
Jul 11, 2002·The American Journal of Cardiology·Pio CasoGeorge R Sutherland
Feb 14, 1998·Phytochemistry·M J LaughlinT W Okita
Feb 17, 1998·International Journal of Cardiology·J E Sanderson
Oct 27, 1997·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·F LarrazetC Veyrat
Oct 25, 2000·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·M HülsmannR Pacher
Jun 3, 1999·American Journal of Respiratory and Critical Care Medicine·P VignonR M Lang
Jan 20, 2009·Anesthesia and Analgesia·François HaddadAndré Y Denault
Apr 27, 2012·Vascular Health and Risk Management·Virginia HeblSantiago Garcia
May 19, 2010·Biomarkers in Medicine·Martin UnverdorbenBernhard R Winkelmann
Apr 12, 2007·Chest·Barbara LichodziejewskaDanuta Liszewska-Pfejfer
Oct 12, 2014·Journal of Pharmacological and Toxicological Methods·Pradtana MeedechRobert L Hamlin
Sep 8, 2009·International Journal of Pediatric Otorhinolaryngology·Ehab Saoud Abd El-MoneimMervat Atya
Jul 1, 2009·Heart Failure Clinics·Vikas K Rathi, Robert W W Biederman
Feb 10, 2009·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Chin-Chang ChengChun-Peng Liu
Oct 29, 2008·Clinics in Chest Medicine·Chee M Chan, James R Klinger
Jul 14, 1998·The American Journal of Cardiology·A Vitarelli, M Gheorghiade
Dec 6, 2005·International Journal of Cardiology·Juan C GrignolaDaniel Guzzo
May 14, 2005·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Jaroslav MeluzinLadislav Dusek
Oct 26, 2005·International Journal of Cardiology·Cheuk-Man YuJohn E Sanderson
Oct 28, 2015·BioMed Research International·Masataka HirataShunji Sano
Oct 26, 2001·The American Journal of Cardiology·C M YuC P Lau
Feb 19, 2015·Cardiovascular Research·Candelas Pérez Del VillarFrancisco Fernández-Avilés
May 16, 2009·JACC. Cardiovascular Imaging·John A SallachAllan L Klein

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiology Journals

Discover the latest cardiology research in this collection of the top cardiology journals.