Right ventricular dysfunction in patients with idiopathic dilated cardiomyopathy: Prognostic value and predictive factors

Archives of Cardiovascular Diseases
Clement VennerYves Juillière

Abstract

Right ventricular (RV) dysfunction is an important predictor of impaired prognosis in idiopathic dilated cardiomyopathy. To determine the prognostic role of RV dysfunction, independent of left ventricular (LV) dysfunction. A total of 136 consecutive patients (73% men; mean age 59.0±13.2 years) with idiopathic dilated cardiomyopathy (LV ejection fraction ≤ 45%) were enrolled retrospectively. Thirty-four patients (25%, group 1) presented with RV dysfunction, defined as tricuspid annular plane systolic excursion (TAPSE) ≤ 15 mm; 102 patients (group 2) had preserved RV function. Mean LV ejection fraction was 27.5±8.7%. Mean TAPSE was 18.6±5.4 mm (15-21.8 mm). Multivariable predictors of RV dysfunction were LV outflow tract time-velocity integral (odds ratio 0.8, 95% confidence interval [CI] 0.7-0.9; P=0.003) and E-wave deceleration time ≤ 145 ms (odds ratio 4.1, 95% CI 1.3-12.8; P=0.017). Major adverse cardiac event-free survival rates at 1 and 2 years were 64% and 55%, respectively, in group 1 and 87% and 79%, respectively, in group 2 (P=0.002). Both by multivariable analysis and after stratification using a propensity score, RV dysfunction emerged as an independent predictor for major adverse cardiac events (hazard ratio 3.2, 95%...Continue Reading

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Citations

Apr 2, 2016·Archives of Cardiovascular Diseases·Pascal de Groote
Sep 8, 2018·The Egyptian Heart Journal : (EHJ) : Official Bulletin of the Egyptian Society of Cardiology·Viola William, Wael El Kilany
Feb 25, 2021·Journal of Veterinary Cardiology : the Official Journal of the European Society of Veterinary Cardiology·T FujiokaY Hidaka
May 12, 2021·Archives of Cardiovascular Diseases·Ariel CohenNicolas Danchin
May 21, 2021·Circulation Journal : Official Journal of the Japanese Circulation Society·Thuy Vy NguyenThuy Duong Ho Huynh
Jul 4, 2020·Internal Medicine Journal·Jun DongJoseph L Nates
Mar 17, 2020·Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'obstétrique Et Gynécologie Du Canada : JOGC·Kelly KuoRinat Hackmon
Oct 17, 2020·Trends in Cardiovascular Medicine·Luna CavigliFlavio D'Ascenzi

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