Right Ventricular Outflow Tract Velocity Time Integral Determination in 570 Healthy Children and in 52 Pediatric Atrial Septal Defect Patients

Pediatric Cardiology
Martin KoestenbergerAndreas Gamillscheg

Abstract

Determination of the right ventricular outflow tract velocity time integral (RVOT VTI) is an important part of the noninvasive investigation of pulmonary blood flow in adults; however, age-related pediatric reference data are lacking. We examined growth-related changes of RVOT VTI values in children and the predictive value of RVOT VTI values in identifying enhanced pulmonary blood flow in children with secundum type atrial septal defect (ASD). A prospective study was conducted in a group of 570 healthy children and 52 children with a moderate-sized to large ASD. We determined the effects of age, body length (BL), body weight (BW), and body surface area (BSA) on RVOT VTI values. The predictive value of normal values stratified for age, BW, BL, and BSA was tested in our 52 ASD children. RVOT VTI values ranged from mean 9.7 ± 1.2 cm in neonates to 23.3 ± 2.7 cm in children with 18 years of age and showed a positive correlation with age, BL, BSA, and BW. In our population, RVOT VTI z-scores showed a high specificity for detecting ASD patients (>97 %) with sensitivity up to 71 %. We provide normal ranges and calculated z-scores of pediatric RVOT VTI values. Normal RVOT VTI z-scores might be additional predictors in identifying incr...Continue Reading

References

Mar 26, 2003·Journal of the American College of Cardiology·Amr E AbbasSteven J Lester
Aug 17, 2010·American Journal of Respiratory and Critical Care Medicine·Jeffrey S ArklesPaul R Forfia
Jul 19, 2013·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Amr E AbbasSteven J Lester
May 2, 2014·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Adriano R TonelliRaed A Dweik

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