Right ventricular systolic dysfunction and remodelling in Nigerians with peripartum cardiomyopathy: a longitudinal study

BMC Cardiovascular Disorders
K M KarayeMichael Y Henein

Abstract

The literature on right ventricular systolic dysfunction (RVSD) in peripartum cardiomyopathy (PPCM) patients is scanty, and it appears that RV reverse remodelling in PPCM has not been previously described. This study thus aimed to assess RVSD and remodelling in a cohort of PPCM patients in Kano, Nigeria. A longitudinal study carried out in 3 referral hospitals in Kano, Nigeria. Consecutive PPCM patients who had satisfied the inclusion criteria were recruited and followed up for 12 months. RVSD was defined as the presence of either tricuspid annular plane systolic excursion (TAPSE) <16 mm or peak systolic wave (S') tissue Doppler velocity of RV free wall <10 cm/s. For the purpose of this study, recovery of RV systolic function was defined as an improvement of reduced TAPSE to ≥ 16 mm or S' to ≥ 10 cm/s, without falling to reduced levels again, during follow-up. A total of 45 patients were recruited over 6 months with a mean age of 26.6 ± 7.0 years. RV systolic function recovery occurred in a total of 8 patients (8/45; 17.8%), of whom 6 (75.0%) recovered in 6 months after diagnosis. The prevalence of RVSD fell from 71.1% at baseline to 36.4% at 6 months (p = 0.007) and 18.8% at 1 year (p = 0.0008 vs baseline; p = 0.41 vs 6 month)...Continue Reading

References

Feb 5, 2003·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·P LindqvistE Kazzam
Dec 10, 2003·Obstetrics and Gynecology·Sara J WhiteheadJeani Chang
Jun 7, 2006·Pulmonary Pharmacology & Therapeutics·Susanna SciomerRoberto Badagliacca
Jun 28, 2006·Journal of Cardiovascular Medicine·Alfredo PosteraroGiancarlo Gambelli
Sep 25, 2007·European Heart Journal·Michele Di MauroSabina Gallina
Feb 14, 2009·Journal of the American College of Cardiology·Wilfried MullensW H Wilson Tang
Aug 3, 2010·European Journal of Heart Failure·Karen SliwaUNKNOWN Heart Failure Association of the European Society of Cardiology Working Group on Peripartum Cardiomyopathy
Mar 19, 2011·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Kamilu M Karaye
Jan 7, 2015·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Roberto M LangJens-Uwe Voigt

❮ Previous
Next ❯

Citations

Oct 21, 2016·Acta Obstetricia Et Gynecologica Scandinavica·Anne S ErsbøllMarianne Johansen
Dec 29, 2016·Circulation. Heart Failure·Sorel GolandJacob George
Mar 7, 2020·Frontiers in Cardiovascular Medicine·Fabrizio RicciSabina Gallina
Oct 23, 2020·BMC Cardiovascular Disorders·Kamilu M KarayeIdris Y Mohammed
Jun 18, 2021·ESC Heart Failure·Kamilu M KarayeUNKNOWN Peripartum Cardiomyopathy in Nigeria (PEACE) Registry Investigators
Nov 14, 2020·Journal of the American College of Cardiology·Kamilu M KarayeUNKNOWN PEACE Registry Investigators

❮ Previous
Next ❯

Software Mentioned

Sonoscape
SPSS

Related Concepts

Related Feeds

Cardiac Remodeling

Cardiac remodeling in response to a myocardial infarction is characterized by progressive ventricular dilatation, cardiac hypertrophy, fibrosis, and deterioration of cardiac performance. Discover the latest research on Cardiac Remodeling here.

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

© 2021 Meta ULC. All rights reserved