Right ventricular systolic function in adolescents and young adults after Mustard operation for transposition of the great arteries

The American Journal of Cardiology
R A HurwitzJ Brown

Abstract

This study evaluates long-term ( > 10 years since surgery) right ventricular (RV) systolic function in patients who had previously undergone intraatrial baffle surgery for transposition of the great arteries. Studies suggest these patients are clinically stable and lead satisfactory lifestyles, but long-term ventricular performance is not known. Radionuclide angiocardiography was used to estimate RV ejection fraction in 58 patients a mean of 14 years after the Mustard operation. Repeat studies were performed in 32 patients. The absolute RV ejection fraction of 0.53 +/- 0.10 in our patients did not differ from normal values. Nine patients had a value < 0.42, placing them > 2 SDs below normal. Repeat RV ejection fraction decreased from 0.54 +/- 0.11 to 0.51 +/- 0.11 (p < 0.1) in 32 patients, and > 0.10 in 6. Thus, RV ejection fraction was abnormal in 9 of 58 patients (16%) evaluated > 10 years after a Mustard operation. Repeat studies demonstrate worsening in at least 6 of 32 patients (19%). These postoperative Mustard patients require continued evaluation, even in the absence of overt symptomatology.

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Citations

Mar 18, 2006·Heart·P A DavlourosM A Gatzoulis
Mar 1, 2000·Cardiology in the Young·K A McLeodW Brawn
Apr 2, 2008·Congenital Heart Disease·Eric S Ebenroth, Roger A Hurwitz
Jan 26, 2002·The American Journal of Cardiology·Eric S Ebenroth, Roger A Hurwitz
Oct 10, 2002·Cardiology Clinics·Tim S HornungAndrew N Redington
Aug 23, 2006·The American Journal of Cardiology·Mary M CanobbioMichael J Landzberg
Nov 26, 2004·Clinical Cardiology·A AgnettiA Frigiola
Dec 14, 2004·International Journal of Cardiology·Aidan P Bolger, Michael A Gatzoulis
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Apr 23, 2005·Cardiology in the Young·Samira S MorhyJose F Ramires
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Nov 27, 2004·Pediatric Cardiology·E C Kirkpatrick, R Hurwitz
Jan 18, 2017·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Evelina A ZimovetzJosephine A Mauskopf

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