PMID: 9422595Jan 9, 1998Paper

RimM and RbfA are essential for efficient processing of 16S rRNA in Escherichia coli

Journal of Bacteriology
Göran O BylundP Mikael Wikström

Abstract

The trmD operon is located at 56.7 min on the genetic map of the Escherichia coli chromosome and contains the genes for ribosomal protein (r-protein) S16, a 21-kDa protein (RimM, formerly called 21K), the tRNA (m1G37)methyltransferase (TrmD), and r-protein L19, in that order. Previously, we have shown that strains from which the rimM gene has been deleted have a sevenfold-reduced growth rate and a reduced translational efficiency. The slow growth and translational deficiency were found to be partly suppressed by mutations in rpsM, which encodes r-protein S13. Further, the RimM protein was shown to have affinity for free ribosomal 30S subunits but not for 30S subunits in the 70S ribosomes. Here we have isolated several new suppressor mutations, most of which seem to be located close to or within the nusA operon at 68.9 min on the chromosome. For at least one of these mutations, increased expression of the ribosome binding factor RbfA is responsible for the suppression of the slow growth and translational deficiency of a deltarimM mutant. Further, the RimM and RbfA proteins were found to be essential for efficient processing of 16S rRNA.

References

Dec 15, 1977·Nature·N KennedyP Herrlich
Oct 24, 1978·Molecular & General Genetics : MGG·R Thompson, M Achtman
Jan 1, 1991·Methods in Enzymology·N KlecknerS Gottesman
Jun 1, 1991·Biochimie·K H Nierhaus
Nov 1, 1991·Molecular Microbiology·C MédigueA Danchin
Apr 1, 1991·Journal of Bacteriology·S KulakauskasD E Berg
Aug 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·R A VanBogelen, F C Neidhardt
Sep 5, 1988·Journal of Molecular Biology·P M WikströmG R Björk
Jan 1, 1987·Annual Review of Biochemistry·G R BjörkP M Wikström
Jan 1, 1987·Methods in Enzymology·K B Mullis, F A Faloona
Jul 1, 1985·The Biochemical Journal·R Brimacombe, W Stiege
Oct 1, 1985·Journal of Bacteriology·P E OrndorffS Falkow
Jun 6, 1973·Nature: New Biology·L Lindahl
Jul 1, 1973·Journal of Bacteriology·R SchleifD Ellis
Sep 1, 1974·Journal of Bacteriology·F C NeidhardtD F Smith
Feb 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·A von GabainS N Cohen
Sep 25, 1995·Biochemical and Biophysical Research Communications·K K MortensenH U Sperling-Petersen
Feb 1, 1993·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·D Apirion, A Miczak
Mar 1, 1994·Molecular Microbiology·P G Jones, M Inouye
Oct 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·J H Alix, M F Guérin
Mar 1, 1996·Molecular Microbiology·J ObertoJ Rouvière-Yaniv

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Citations

Jan 28, 2003·Biopolymers·Gloria M Culver
Jul 11, 2006·Journal of Molecular Microbiology and Biotechnology·Koichi InoueMasayori Inouye
Jul 10, 2007·Journal of Bacteriology·Sakura SuzukiShigeyuki Yokoyama
Feb 24, 2010·Proceedings of the National Academy of Sciences of the United States of America·Biswajoy Roy-ChaudhuriGloria M Culver
Jun 14, 2014·Frontiers in Plant Science·Alexandra-Viola Bohne
Apr 20, 2018·The EMBO Journal·José M AndradeCecília M Arraiano
Sep 7, 2007·Microbiology and Molecular Biology Reviews : MMBR·Magdalena Kaczanowska, Monica Rydén-Aulin
Sep 19, 2006·Journal of Bacteriology·Mengxi JiangJanine R Maddock
Nov 26, 2010·The EMBO Journal·Simon GotoHyouta Himeno
Sep 30, 2016·Microbiology and Molecular Biology Reviews : MMBR·Daniel R ReußJörg Stülke
Sep 15, 2019·Nature Communications·Raphaël MéheustJillian F Banfield
Jan 21, 2003·Journal of Bacteriology·Glenn R Björk, Kristina Nilsson
Jun 15, 2007·Critical Reviews in Biochemistry and Molecular Biology·Daniel N Wilson, Knud H Nierhaus
Jun 2, 2016·Infection and Immunity·Shinya WatanabeTeruo Kirikae
Jul 17, 2020·Biomolecular NMR Assignments·Andreas SchedlbauerSean R Connell
Aug 22, 2006·Nucleic Acids Research·Martine RooversLouis Droogmans
May 3, 2011·Annual Review of Biochemistry·Zahra ShajaniJames R Williamson
Nov 8, 2008·Molecular Microbiology·Keith ConnollyGloria Culver
May 3, 2012·TheScientificWorldJournal·Michael KubeErich Seemüller
May 10, 2008·Molecular Microbiology·Biswajoy Roy-ChaudhuriGloria M Culver
May 18, 2017·The Biochemical Journal·Agata RozanskaRobert N Lightowlers
Feb 22, 2018·Journal of Bacteriology·Kayley H JanssenTimothy L Yahr
Sep 17, 2018·Nucleic Acids Research·Chaitanya Jain
Jan 16, 2021·The Plant Journal : for Cell and Molecular Biology·Chunhui XuBao-Cai Tan

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