PMID: 2510260Jan 1, 1989Paper

Rioprostil, a new prostaglandin E1 analogue, in the once-daily treatment for the prevention of duodenal ulcer recurrence: a comparison with ranitidine

Scandinavian Journal of Gastroenterology. Supplement
J A BusingerH Stocker

Abstract

The efficacy of Rioprostil (a new prostaglandin E1 analogue) is compared with that of ranitidine in the recurrence prevention of duodenal ulcer(s). Duration of treatment is 6 months. Ninety-seven patients received rioprostil, 600 micrograms once-daily orally, and 110 patients received ranitidine, 150 mg once-daily orally. On rioprostil, 14.9% of patients showed a relapse after 6 months compared to 10.1% on ranitidine. Diarrhoea occurred in 7 patients on rioprostil and 3 patients on ranitidine. Rioprostil given 600 micrograms daily in the evening is a highly effective treatment for the prevention of duodenal ulcer relapse, the efficacy not being significantly different from ranitidine 150 mg.

References

Jan 15, 1985·Klinische Wochenschrift·J SchraderF Scheler
Nov 1, 1972·Computer Programs in Biomedicine·E T Lee, M M Desu

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Citations

Jan 1, 1989·Scandinavian Journal of Gastroenterology. Supplement·H G DammannB Simon

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