Rising trends in pancreatic cancer incidence and mortality in 2000-2014

Clinical Epidemiology
Wenrui WuLanjuan Li

Abstract

The morbidity and mortality of pancreatic cancer vary considerably around the world. The aim of this study was to characterize and evaluate recent changes in incidence and incidence-based mortality in the USA. Incidence and incidence-based mortality data were based on the 18 Surveillance, Epidemiology, and End Results (SEER) registries through SEER*Stat software. We adopted joinpoint regression to analyze the temporal trends stratified by age, gender, ethnicity, stage, tumor site, and size. Based on 18 SEER data sets, the age-adjusted incidence of pancreatic cancer increased from 11.85/100,000 in 2000 to 14.70/100,000 in 2014, increasing by an average annual percentage change (AAPC) of 1.6 (95% CI 1.5-1.8, p<0.05). The incidence-based mortality also increased, from 9.96/100,000 in 2001 to 12.96/100,000 in 2014, increasing by an AAPC of 1.9 (95% CI 1.3-2.5, p<0.05). However, we observed a deceleration in mortality since 2005, with the annual percentage change decreasing from 4.1 (2001-2005) to 1.0 (2005-2014). These increasing trends in pancreatic cancer were observed in most subgroups (stratified by age, gender, ethnicity, stage, tumor site, and size). The incidence and mortality rates of pancreatic cancer in the USA have incre...Continue Reading

Citations

Oct 16, 2019·Chembiochem : a European Journal of Chemical Biology·Jing ZhangShige Wang
Sep 2, 2020·The American Surgeon·Elissa C DaltonGregory J Tiesi
Jun 12, 2019·Journal of Medical Case Reports·Milton Rahman, Letora Washington
Aug 7, 2019·Journal of Gastrointestinal Cancer·Fatemeh Hadavand Siri, Hamid Salehiniya
Jul 21, 2020·The American Surgeon·Elissa C DaltonGregory G Tiesi
Sep 2, 2020·ANZ Journal of Surgery·Savio George Barreto, Katina D'Onise
Nov 4, 2020·Annals of Surgical Oncology·Rebecca S MeltzerMihir M Shah
Mar 30, 2020·Cancer Research·Christopher GromischMark W Grinstaff
Feb 20, 2021·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Hiroshi ImaokaJunji Furuse
Mar 29, 2021·Journal of Controlled Release : Official Journal of the Controlled Release Society·Yu HangDavid Oupický
Apr 24, 2021·Medical Oncology·Devashish DesaiRashmika Potdar
May 19, 2021·Cancer Causes & Control : CCC·Edgar CoronaFolasade P May
Jun 25, 2021·World Journal of Gastroenterology : WJG·Nikhil Gupta, Raghav Yelamanchi
Oct 16, 2020·Gastroenterology·Junjie HuangMartin C S Wong
Aug 7, 2021·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Marlon J BrewerAimee L Lucas
Oct 2, 2021·Current Treatment Options in Oncology·Arthur Winer, Efrat Dotan

❮ Previous
Next ❯

Software Mentioned

SEER
Joinpoint
Stat

Related Concepts

Related Feeds

Adenomatous Polyposis Coli

Adenomatous polyposis coli is a protein encoded by the APC gene and acts as a tumor suppressor. Discover the latest research on adenomatous polyposis coli here.

Related Papers

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology
Richard M HoffmanCharles L Wiggins
Revista médica de Chile
Solange Núñez-GonzálezDaniel Simancas-Racine
Journal of B.U.ON. : Official Journal of the Balkan Union of Oncology
Tamara NaumovicZivko Perisic
© 2022 Meta ULC. All rights reserved