Risk adjustment performance of Charlson and Elixhauser comorbidities in ICD-9 and ICD-10 administrative databases

BMC Health Services Research
Bing LiHude Quan

Abstract

The performance of the Charlson and Elixhauser comorbidity measures in predicting patient outcomes have been well validated with ICD-9 data but not with ICD-10 data, especially in disease specific patient cohorts. The objective of this study was to assess the performance of these two comorbidity measures in the prediction of in-hospital and 1 year mortality among patients with congestive heart failure (CHF), diabetes, chronic renal failure (CRF), stroke and patients undergoing coronary artery bypass grafting (CABG). A Canadian provincial hospital discharge administrative database was used to define 17 Charlson comorbidities and 30 Elixhauser comorbidities. C-statistic values were calculated to evaluate the performance of two measures. One year mortality information was obtained from the provincial Vital Statistics Department. The absolute difference between ICD-9 and ICD-10 data in C-statistics ranged from 0 to 0.04 across five cohorts for the Charlson and Elixhauser comorbidity measures predicting in-hospital or 1 year mortality. In the models predicting in-hospital mortality using ICD-10 data, the C-statistics ranged from 0.62 (for stroke) - 0.82 (for diabetes) for Charlson measure and 0.62 (for stroke) to 0.83 (for CABG) for...Continue Reading

References

Feb 7, 1998·Medical Care·A ElixhauserR M Coffey
Dec 2, 1999·Journal of Clinical Epidemiology·S E GabrielW M O'Fallon
Jun 24, 2003·Health Policy·Florian Buchner, Jürgen Wasem
Aug 22, 2003·International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care·L I Iezzoni
Dec 25, 2004·Journal of Clinical Epidemiology·Vijaya SundararajanWilliam A Ghali
Oct 7, 2005·Arthritis and Rheumatism·Kelli L DominickHayden B Bosworth
Aug 10, 2006·Journal of Clinical Epidemiology·David B PreenKate J Brameld
Nov 17, 2007·Medical Care·Vijaya SundararajanUNKNOWN International Methodology Consortium for Coded Health Information (IMECCHI)

❮ Previous
Next ❯

Citations

Feb 18, 2011·JAMA : the Journal of the American Medical Association·Karen E JoyntAshish K Jha
Oct 11, 2011·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Laura HaasJonas Schreyoegg
Aug 16, 2008·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Robert W EppsteinerShimul A Shah
Oct 6, 2011·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Elan R WitkowskiJennifer F Tseng
Apr 26, 2013·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·David R WilliamsonDanielle Pilon
Mar 30, 2012·The New England Journal of Medicine·Ashish K JhaArnold M Epstein
Jun 24, 2010·Annals of Surgery·Todd R VogelStephen F Lowry
May 13, 2011·Annals of Surgery·Benjamin D Kozower, George J Stukenborg
Dec 16, 2010·Circulation. Cardiovascular Quality and Outcomes·Karen E Joynt, Ashish K Jha
Mar 6, 2010·BMC Cardiovascular Disorders·Guanmin ChenHude Quan
Jun 15, 2011·BMC Health Services Research·Jacqueline M QuailGary F Teare
Sep 26, 2013·BMC Health Services Research·Lisa M LixGary F Teare
Feb 13, 2013·BMC Health Services Research·Gabriele MessinaNicola Nante
Apr 8, 2009·Journal of Preventive Medicine and Public Health = Yebang Ŭihakhoe Chi·Min Ho KyungHyeung-Keun Park
Aug 14, 2009·Journal of Preventive Medicine and Public Health = Yebang Ŭihakhoe Chi·Kyoung Hoon Kim, Lee Su Ahn
Jul 20, 2011·Journal of Emergencies, Trauma, and Shock·Kenneth A EgolKenneth J Koval
Jul 12, 2013·Journal of the American Medical Informatics Association : JAMIA·Stuart M SpeedieDonald P Connelly
Mar 29, 2014·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·C ReyesD Prieto-Alhambra
Oct 6, 2014·The Annals of Thoracic Surgery·Laura SchneiderChristian J Finley
Mar 15, 2014·Cardiovascular Journal of Africa·Thomas A Mabin, Pascal Condolfi
Jan 20, 2016·The American Journal of Gastroenterology·Sumant InamdarArvind J Trindade
Sep 18, 2012·PM & R : the Journal of Injury, Function, and Rehabilitation·Jeffrey C SchneiderRoss Zafonte
May 1, 2012·The Annals of Thoracic Surgery·Benjamin D Kozower, George J Stukenborg
Jan 11, 2012·The Canadian Journal of Cardiology·Laurie LambertPeter Bogaty
Jun 22, 2011·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Skye C MayoTimothy M Pawlik
Jun 28, 2011·The Annals of Thoracic Surgery·Christian J FinleyGail Darling
Sep 21, 2010·The Journal of Thoracic and Cardiovascular Surgery·Christian J FinleyGail E Darling
Dec 31, 2015·Journal of the American Medical Directors Association·Robert E BurkeAdit A Ginde
May 9, 2015·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Sumant InamdarArvind J Trindade
Feb 21, 2009·Journal of the American College of Surgeons·Nicholas G CsikeszShimul A Shah
Jul 10, 2012·Methods of Information in Medicine·Gregor Stiglic, P Kokol
Apr 29, 2015·Journal of General Internal Medicine·Ishak MansiEric M Mortensen

❮ Previous
Next ❯

Methods Mentioned

BETA
coronary artery bypass

Software Mentioned

CIHI

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.