PMID: 3612782Jun 1, 1987

Risk-factor changes in wives with husbands at high risk of coronary heart disease (CHD): the spin-off effect

Journal of Behavioral Medicine
M SextonN Wright


This study of 220 wives of participants from four of the 22 clinics in the Multiple Risk Factor Intervention Trial (MRFIT) addresses the question of whether spouses of men exposed to a continuous coronary heart disease (CHD) risk-factor intervention program (SI group) make changes in their own risk status compared to wives of men who did not receive the intervention program (UC group). Total serum cholesterol and low-density lipoprotein (LDL) cholesterol were significantly lower for the SI wives. These differences were found for both hypertensive and normotensive wives, although the magnitudes were much greater for the hypertensive wives. There were also significant differences between the two groups of wives in the food-record rating and in dietary-knowledge scores, indicating that the probable mechanism for the beneficial effect of the intervention with respect to cholesterol levels was the change in the family diet. Although not statistically significant, differences indicating a lower risk for SI wives were found for diastolic blood pressure. There was also a greater mean reduction in cigarettes per day for SI wives who smoked.


Oct 1, 1983·American Journal of Epidemiology·T L Bush, G W Comstock
Feb 1, 1980·American Journal of Public Health·M A Ibrahim
Feb 1, 1980·American Journal of Public Health·S G Haynes, M Feinleib


Jan 1, 1988·Social Science & Medicine·R S ZimmermanJ Benezra
Oct 11, 2003·Appetite·Jeffery Sobal, Mary K Nelson
Sep 10, 2002·Journal of Nutrition Education and Behavior·J Lynne Brown, Daisy Miller
Sep 3, 2008·International Journal of Obesity : Journal of the International Association for the Study of Obesity·A A GorinLook AHEAD Home Environment Research Group
Sep 21, 2002·BMJ : British Medical Journal·Julia Hippisley-CoxVicky Hammersley
Jul 19, 2013·Journal of Aging and Health·Rachel Margolis
Jan 11, 2013·American Journal of Health Promotion : AJHP·Megan A LewisJulia Kish-Doto
Jan 28, 2014·BMC Medicine·Aaron LeongKaberi Dasgupta
Sep 1, 1992·American Journal of Public Health·A L ShattuckA R Kristal
Oct 11, 2008·American Journal of Epidemiology·Augusto Di CastelnuovoLicia Iacoviello
Mar 20, 2012·Social Science & Medicine·Matthew C AalsmaJ Dennis Fortenberry
Jan 1, 1990·Psychosomatics·S B Shanfield
Oct 27, 2011·Journal of the American Dietetic Association·Raffaella RossiniGiulio Marchesini
Jun 12, 2010·Annals of Epidemiology·Chih-Wen PaiDee W Edington
May 6, 2003·Journal of Marital and Family Therapy·Thomas L Campbell
Sep 9, 2005·Social Science & Medicine·Megan A LewisKaren M Emmons
Dec 13, 2005·Cancer Letters·Narasimhan RagavanFrancis L Martin
Nov 30, 2018·Diabetic Medicine : a Journal of the British Diabetic Association·P M TriefR S Weinstock
Jul 29, 2006·Arthritis and Rheumatism·Megan A LewisRobert F DeVellis
Oct 28, 2009·International Journal of Obesity : Journal of the International Association for the Study of Obesity·T MatsuoK Tanaka

Related Concepts

Attitude to Health
Diastolic Blood Pressure
Coronary Heart Disease
Relative Risk
Cigar smoker

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Systemic Juvenile Idiopathic Arthritis

Systemic juvenile idiopathic arthritis is a rare rheumatic disease that affects children. Symptoms include joint pain, but also fevers and skin rashes. Here is the latest on this disease.

Chromatin Regulation and Circadian Clocks

The circadian clock plays an important role in regulating transcriptional dynamics through changes in chromatin folding and remodelling. Discover the latest research on Chromatin Regulation and Circadian Clocks here.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Pontocerebellar Hypoplasia

Pontocerebellar hypoplasias are a group of neurodegenerative autosomal recessive disorders with prenatal onset, atrophy or hypoplasia of the cerebellum, hypoplasia of the ventral pons, microcephaly, variable neocortical atrophy and severe mental and motor impairments. Here is the latest research on pontocerebellar hypoplasia.

Cell Atlas Along the Gut-Brain Axis

Profiling cells along the gut-brain axis at the single cell level will provide unique information for each cell type, a three-dimensional map of how cell types work together to form tissues, and insights into how changes in the map underlie health and disease of the GI system and its crosstalk with the brain. Disocver the latest research on single cell analysis of the gut-brain axis here.

Chronic Traumatic Encephalopathy

Chronic Traumatic Encephalopathy (CTE) is a progressive degenerative disease that occurs in individuals that suffer repetitive brain trauma. Discover the latest research on traumatic encephalopathy here.