Risk factors affecting hospital stay among patients undergoing colon cancer surgery: a prospective cohort study

Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer
Miren OriveREDISSEC-CARESS/CCR group

Abstract

To identify and validate risk factors that contribute to prolonged length of hospital stay (LOS) in patients undergoing resection for colorectal cancer. This prospective cohort study included 1955 patients admitted to 22 hospitals for primary resection of colorectal cancer. Multivariate analyses were used to identify and validate risk factors, randomizing patients into a derivation and a validation cohort. Multiple correspondence and cluster analysis were performed to identify clinical subtypes based on LOS. The strongest independent predictors of prolonged LOS were postoperative reintervention, surgical site infection, open surgery, and distant metastasis. The multiple correspondence and cluster analysis provided three groups of patients in relation to prolonged LOS: patients with the longest LOS included the highest percentage of patients with open surgery, distant metastasis, deep surgical site infections, emergency admissions, additional diagnostic factors, and highly contaminated surgical sites. Patients with prolonged LOS (> 14 days) were more likely to develop adverse outcomes within 30 days after discharge. Patients undergoing resection of colorectal cancer cluster into different groups based on LOS of the index admissi...Continue Reading

Associated Clinical Trials

Jul 2, 2015·JOSE M QUINTANA-LOPEZ, MD PhD

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Sep 20, 2015·Statistical Methods in Medical Research·Irantzu BarrioJosé-María Quintana

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Citations

May 3, 2019·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Anna Vittoria MattioliRoberta Gelmini
Aug 31, 2019·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Miren OriveJose Maria Quintana
Jul 3, 2021·Current Oncology·Keegan GuidolinAshlie Nadler

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