Risk Factors Affecting the Prognosis of Descending Necrotizing Mediastinitis From Odontogenic Infection

Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
Luyao QuXieyi Cai

Abstract

Descending necrotizing mediastinitis (DNM) is a serious complication of head and neck infections and has an excessively high mortality rate owing to the lack of understanding of DNM. We assessed the clinical characteristics, diagnosis, treatment, and outcomes of odontogenic DNM and evaluated the risk factors affecting the prognosis of DNM to provide an up-to-date overview for clinical practice. We performed a retrospective cohort study, enrolling a sample of patients with DNM due to odontogenic infection who had been referred from January 2013 to December 2016. The patients were classified into surviving and deceased groups. The primary predictors in the present study were the presence of multiple comorbidities, complications, demographic data (age, gender), laboratory tests (white blood cell count, percentage of neutrophils), and time (duration before diagnosis, length of hospital stay). The primary outcome variable was the patient outcome (dead or alive). The continuous variables were evaluated using Student's t test or the t test, and the categorical and binary variables were compared using the χ2 test or Fisher exact test. A total of 81 patients (68 men, 13 women; median age of 57.2 ± 12.2 years) were included. The mortalit...Continue Reading

Citations

Aug 14, 2020·Clinical Oral Investigations·Niina RautaporrasJohanna Snäll
Feb 26, 2020·Surgical Infections·Ahmed Gaber HassaneinAsmaa El Sayed Mohammed El Sayed
Dec 13, 2019·Case Reports in Dentistry·Eugênia Leal de FigueiredoRicardo José de Holanda Vasconcellos
Dec 11, 2020·Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale·Maria Luisa FiorellaNicola Quaranta
Nov 25, 2020·The British Journal of Oral & Maxillofacial Surgery·N GallagherC M Bowe
Mar 15, 2021·Archivos de bronconeumología·Carmen Sánchez-MatásMercedes Jiménez-Sánchez
May 19, 2021·The British Journal of Oral & Maxillofacial Surgery·M F EscobedoS Junquera
Jun 10, 2021·Medicina clínica·José López-FernándezIsmael Antón Fernández
Jul 12, 2021·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Eleni PararaGeorge Rallis

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