Risk factors and etiology of surgical site infection after radical neck dissection in patients with head and neck cancer

The Korean Journal of Internal Medicine
So Yeon ParkYoung Soo Rho

Abstract

Surgical site infection (SSI) is a major complication after radical neck dissection (RND) in patients with head and neck cancer (HNC). We investigated the incidence, risk factors, and etiology of SSI among patients who underwent RND. A retrospective cohort study was performed on HNC patients, excluding those with thyroid cancer, who underwent first RND at a teaching hospital between January 2006 and June 2010. Medical records were collected and analyzed to evaluate the risk factors and microbiological etiologies. A total of 370 patients underwent first RND. The overall incidence of SSI was 19.7% (73/370). Multivariate analysis showed that male sex (odds ratio [OR], 4.281; p = 0.004), cardiovascular diseases (OR, 1.941; p = 0.020), large amount of blood loss during surgery (OR, 4.213; p = 0.001), and surgery lasting longer than 6 hours (OR, 4.213; p = 0.002) were significantly associated with SSI. The most common causative pathogen was Staphylococcus aureus (32.6%), and 93.2% of S. aureus isolates were methicillin-resistant. Klebsiella pneumoniae (13/92, 14.1%), Pseudomonas aeruginosa (11/92, 12.0%), and Enterococcus species (11/92, 12.0%) were also frequently detected. Based on our results, we predict that certain groups of pat...Continue Reading

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Citations

Feb 23, 2018·World Journal of Surgery·F A SalemA Bergenfelz
Apr 3, 2019·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Zaid Al-QurayshiEmad Kandil
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Mar 31, 2021·Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'oto-rhino-laryngologie Et De Chirurgie Cervico-faciale·Tai-Yu ChenYi-Chan Lee
Sep 22, 2021·CA: a Cancer Journal for Clinicians·Amila K NanayakkaraDavid E Greenberg

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Methods Mentioned

BETA
dissection

Software Mentioned

SPSS

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