Risk Factors and Outcome of Acute Kidney Injury after Isolated CABG Surgery: a Prospective Cohort Study

Brazilian Journal of Cardiovascular Surgery
Shahram AminiMahdieh Jafari

Abstract

Acute kidney injury (AKI) is a frequent event after cardiac surgery with increased mortality and morbidity. We explored frequency, risk factors, and associated morbidity and mortality of AKI after isolated coronary artery bypass grafting (CABG) surgery at a single institution. All consecutive adults undergoing CABG surgery from March 2013 to October 2016 were assessed for development and severity of AKI based on Acute Kidney Injury Network (AKIN) criteria. The patients were also investigated regarding their need for renal replacement therapy (RRT), predictive risk factors, and associated outcomes, including duration of mechanical ventilation, mortality, intensive care unit (ICU) and hospital length of stay. Of 1737 patients in the study, 275 (15.8%) developed AKI. Twenty-five (12.8%) cases required RRT. Patients with AKI had longer ventilation time, ICU and hospital length of stay (P<0.001). Mortality rates were 28 (10.2%) and 22 (1.5%) in patients with and without AKI, respectively (P<0.001). There was a strong association between advanced age (aOR=1.016, 95% CI=1.002-1.030, P=0.028), diabetes (aOR=1.36, 95% CI=1.022-1.809, P=0.035), on-pump surgery (aOR=2.63, 95% CI=1.543-4.483, P<0.001), transfusion of more than 1 unit of re...Continue Reading

Citations

Jun 11, 2020·Journal of Clinical Medicine·Charat ThongprayoonWisit Cheungpasitporn
Dec 15, 2020·AACN Advanced Critical Care·Lori Dugan BrienCatherine Tierney
Aug 23, 2021·Journal of Cardiothoracic and Vascular Anesthesia·Gabriela PetteyPalesa Motshabi Chakane

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Methods Mentioned

BETA
coronary artery bypass

Software Mentioned

SPSS

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