Risk factors associated with exposure to bovine respiratory disease pathogens during the peri-weaning period in dairy bull calves

BMC Veterinary Research
Gerard M MurrayJoseph P Cassidy

Abstract

Bovine respiratory disease (BRD) remains among the leading causes of death of cattle internationally. The objective of this study was to identify risk factors associated with exposure to BRD pathogens during the peri-weaning period (day (d)-14 to d 14 relative to weaning at 0) in dairy bull calves using serological responses to these pathogens as surrogate markers of exposure. Clinically normal Holstein-Friesian and Jersey breed bull calves (n = 72) were group housed in 4 pens using a factorial design with calves of different breeds and planes of nutrition in each pen. Intrinsic, management and clinical data were collected during the pre-weaning (d - 56 to d - 14) period. Calves were gradually weaned over 14 days (d - 14 to d 0). Serological analysis for antibodies against key BRD pathogens (BRSV, BPI3V, BHV-1, BHV-4, BCoV, BVDV and H. somni) was undertaken at d - 14 and d 14. Linear regression models (for BVDV, BPI3V, BHV-1, BHV-4, BCoV and H. somni) and a single mixed effect random variable model (for BRSV) were used to identify risk factors for changes in antibody levels to these pathogens. BRSV was the only pathogen which demonstrated clustering by pen. Jersey calves experienced significantly lower changes in BVDV S/P than ...Continue Reading

References

Jan 1, 1970·Clinica Chimica Acta; International Journal of Clinical Chemistry·A D McEwanW J Penhale
Feb 1, 1994·Immunology Today·H Baumann, J Gauldie
Sep 11, 1993·The Veterinary Record·K MaatjeT S van den Ingh
Aug 3, 2002·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Mustafa HasoksuzLinda J Saif
Jan 25, 2005·Acta Veterinaria Scandinavica·H HärtelH Saloniemi
Nov 16, 2006·Journal of Dairy Science·C SvenssonS-O Olsson
Jan 26, 2008·Animal Health Research Reviews·S M DaboA W Confer
Mar 12, 2009·Omics : a Journal of Integrative Biology·Palok AichPhilip Griebel
May 19, 2009·Journal of Dairy Science·S M GulliksenO Osterås
Nov 10, 2009·Comparative Immunology, Microbiology and Infectious Diseases·Toomas OrroTimo Soveri
Jul 14, 2010·The Veterinary Clinics of North America. Food Animal Practice·Mark R AckermannJames A Roth
May 31, 2011·Veterinary Immunology and Immunopathology·Elizabeth J GlassOliver C Jann
May 1, 2012·Journal of Dairy Science·M BrscicC G Van Reenen
Feb 13, 2014·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·S Jo MooreAmanda J O'Hara
Nov 21, 2014·Animal Health Research Reviews·Sheila M McGuirk, Simon F Peek
Feb 25, 2015·American Journal of Veterinary Research·M Claire WindeyerStephen J LeBlanc
Sep 19, 2015·Veterinary Microbiology·Pelin Tuncer, Kadir Yeşilbağ
Jan 12, 2017·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Gerard M MurrayJoseph P Cassidy
Jul 13, 2017·The Veterinary Journal·M Claire WindeyerHerman Barkema

❮ Previous
Next ❯

Citations

Jan 20, 2020·Journal of Dairy Science·B PardonS Ribbens
Oct 4, 2020·Animals : an Open Access Journal From MDPI·Miguel FernándezValentín Pérez
Sep 26, 2020·Preventive Veterinary Medicine·John I AlawnehTimothy W J Olchowy

❮ Previous
Next ❯

Methods Mentioned

BETA
enzyme-linked immunosorbent assays
ELISA
MDA

Software Mentioned

Stata

Related Concepts