Abstract
Data on risk factors for portomesenteric venous thrombosis (PMVT) following abdominal surgery for ulcerative colitis (UC) are limited. The aim of this study was to investigate factors associated with PMVT after surgical treatment for UC. Patients who underwent restorative proctocolectomy (RPC) and ileal pouch-anal anastomosis (IPAA) including diverting ileostomy closure for medically refractory UC were identified from a prospectively maintained database. Patient-related, disease-related and treatment-related variables were collected. Univariable and multivariable analyses were performed to assess factors associated with PMVT. Of the 521 patients completing surgical treatment for UC between 2006 and 2012, symptomatic PMVT occurred in 36 (7%), which resulted in a significantly increased hospital stay (P < 0.001). Patients developing PMVT were younger (P = 0.014), had a lower preoperative albumin level (P = 0.037) and were more likely to have been taking steroids within 1 month before surgery (P = 0.006). The combined incidence of PMVT was comparable between patients having a three-stage and two-stage management (6% vs. 8%, P = 0.43), but the relative incidence of PMVT after RPC + IPAA was 8%, significantly higher than the 4% afte...Continue Reading
References
Feb 28, 1998·Surgical Endoscopy·J JakimowiczF Smulders
Jan 7, 2000·Journal of the American College of Surgeons·L M FarkasH Abcarian
Jun 14, 2000·Journal of Hepatology·D C Valla, B Condat
Aug 5, 2000·QJM : Monthly Journal of the Association of Physicians·C L SheenJ K Ramage
Jan 5, 2002·The New England Journal of Medicine·S KumarP S Kamath
Oct 31, 2002·Surgery·Feza H RemziDavid Einstein
Mar 5, 2003·Radiology·Mark E BakerVictor Fazio
Jun 7, 2003·Diseases of the Colon and Rectum·Alessandro FicheraTomas M Heimann
Nov 8, 2005·Thrombosis and Haemostasis·Bernd JilmaAndrew D Blann
Feb 14, 2006·Gut·S VermeireP Rutgeerts
May 8, 2007·Journal of the American College of Surgeons·Chelliah R SelvasekarJohn H Pemberton
Jun 27, 2007·Surgery Today·Chad G BallEarl L Raber
Aug 19, 2007·Diseases of the Colon and Rectum·M MillanF Remzi
Jun 10, 2008·Diseases of the Colon and Rectum·I J MorF H Remzi
Jan 10, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·P H E TeeuwenR P Bleichrodt
Apr 10, 2009·The British Journal of Surgery·G S El-GazzazD P Geisler
Jun 17, 2009·Archives of Surgery·Aaron W JamesGuilherme M Campos
Mar 17, 2011·The American Journal of Gastroenterology·Sanjay K Murthy, Geoffrey C Nguyen
May 3, 2011·Surgical Endoscopy·Jinyu GuRavi P Kiran
Feb 15, 2012·Chest·Clive KearonSusan R Kahn
Nov 7, 2012·Journal of Crohn's & Colitis·Pavol PapayGottfried Novacek
May 1, 2013·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·J GuR P Kiran
Oct 10, 2013·Diseases of the Colon and Rectum·Jinyu GuRavi P Kiran
Nov 8, 2013·Surgical Endoscopy·Jinyu GuRavi P Kiran
Nov 19, 2013·World Journal of Surgery·Marco E AllaixAlessandro Fichera
Citations
Jan 24, 2019·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Myung Jo KimSung-Bum Kang
Sep 1, 2018·Annals of Surgery·Nicholas P McKennaElizabeth B Habermann
Aug 26, 2017·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Nicholas P McKennaAmy L Lightner
Aug 25, 2020·Internal Medicine·Takeshi YasudaYoshito Itoh
Aug 3, 2019·Inflammatory Bowel Diseases·Maia KayalMarla C Dubinsky
Nov 5, 2019·The Surgical Clinics of North America·Lea Lowenfeld, Kyle G Cologne
May 21, 2021·BMC Surgery·Norimitsu ShimadaShinya Takahashi
May 5, 2021·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Amy L LightnerPhillip R Fleshner
Oct 29, 2017·American Journal of Surgery·Emre GorgunConor P Delaney
Oct 13, 2021·Diseases of the Colon and Rectum·Maitri Patel, Traci Hedrick