Risk factors associated with the isolation of colistin-resistant gram-negative bacteria: a matched case-control study

Critical Care Medicine
Dimitrios K MatthaiouMatthew E Falagas

Abstract

The emergence of multidrug-resistant gram-negative bacteria has led to the re-use of colistin, but resistance to this agent has already been reported. We aimed to investigate the potential risk factors for the isolation of colistin-resistant Klebsiella pneumoniae, Acinetobacter baumannii, and Pseudomonas aeruginosa from hospitalized patients. Matched case-control study. Tertiary care hospital in Athens, Greece. Case patients were those who had provided a clinical specimen from which a colistin-resistant K. pneumoniae, A. baumannii, or P. aeruginosa was isolated. Controls were selected from a pool of patients who had susceptible to colistin isolates and were matched (1:1) to cases for species of microorganism and site of isolation. Susceptibility to colistin was determined with the Etest. None. Data regarding patient demographics, comorbidities, admission to the intensive care unit, prior antibiotic use, and invasive procedures performed were analyzed as risk factors in a matched bivariable model. Variables significantly associated with colistin-resistant isolates (p < .05) were entered in a backward multivariable logistic regression model. Forty-one colistin-resistant unique patient isolates were identified from January 1, 2006...Continue Reading

References

Oct 1, 1984·Antimicrobial Agents and Chemotherapy·R A MooreR E Hancock
Nov 26, 1997·Journal of Bacteriology·E A GroismanF C Soncini
Aug 5, 2000·Respiratory Medicine·J M LittlewoodF Duncan-Skingle
Feb 15, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J H RexJ E Edwards
Mar 27, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·A D HarrisM H Samore
May 29, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Anthony D HarrisYehuda Carmeli
Feb 27, 2003·Antimicrobial Agents and Chemotherapy·Charles R DeanPatricia A Bradford
Oct 31, 2003·The Journal of Antimicrobial Chemotherapy·Jian LiJohn Turnidge
Dec 29, 2004·International Journal of Antimicrobial Agents·Jian LiKingsley Coulthard
Apr 12, 2005·BMC Infectious Diseases·Matthew E FalagasArgyris Michalopoulos
Apr 13, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Matthew E Falagas, Sofia K Kasiakou
May 11, 2005·The Journal of Antimicrobial Chemotherapy·David LandmanJohn Quale
Aug 30, 2005·Antimicrobial Agents and Chemotherapy·Vincent H TamRussell E Lewis
Feb 1, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·George H TalbotUNKNOWN Antimicrobial Availability Task Force of the Infectious Diseases Society of America
Aug 26, 2006·The Lancet Infectious Diseases·Jian LiDavid L Paterson
Aug 31, 2006·Antimicrobial Agents and Chemotherapy·Jian LiLisa Liolios
Aug 31, 2006·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Matthew E FalagasArgyris Michalopoulos
Feb 20, 2007·International Journal of Antimicrobial Agents·Matthew E Falagas, Ioannis A Bliziotis
Feb 20, 2007·The Journal of Antimicrobial Chemotherapy·Anastasia AntoniadouHelen Giamarellou
Mar 14, 2007·The Journal of Antimicrobial Chemotherapy·Shiri Navon-VeneziaYehuda Carmeli
Mar 21, 2007·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·T Y Tan, S Y Ng

❮ Previous
Next ❯

Citations

Jul 4, 2012·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·G SamonisM E Falagas
Jul 30, 2011·Current Infectious Disease Reports·Håkan HanbergerHelen Giamarellou
Aug 7, 2010·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Cheng-Chih LinChun-Ming Lee
Jul 30, 2011·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Maria Rosalia PascaPiero Marone
Feb 11, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M E Falagas, Petros I Rafailidis
Apr 26, 2008·The Journal of Antimicrobial Chemotherapy·Drosos E KarageorgopoulosMatthew E Falagas
Mar 20, 2010·The Journal of Antimicrobial Chemotherapy·Mical PaulLeonard Leibovici
Oct 3, 2009·Current Opinion in Infectious Diseases·Roger L Nation, Jian Li
Jun 17, 2009·Antimicrobial Agents and Chemotherapy·Mark D AdamsRobert A Bonomo
Dec 14, 2012·Annals of Clinical Microbiology and Antimicrobials·Grace C Lee, David S Burgess
Jan 12, 2013·Antimicrobial Resistance and Infection Control·Jean Carlet, Didier Pittet
Jun 26, 2009·Drugs & Aging·Georgios PappasMatthew E Falagas
Sep 15, 2009·Drugs·Helen Giamarellou, Garyphallia Poulakou
Jun 29, 2011·Future Microbiology·Matthew E FalagasPatrice Nordmann
Oct 12, 2010·Journal of Global Infectious Diseases·Vikas ManchandaNp Singh
May 25, 2013·Future Microbiology·Tony VelkovJian Li
Sep 14, 2013·Journal of Postgraduate Medicine·A K Dhariwal, M S Tullu
Jan 25, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Hanna SidjabatDavid L Paterson
May 7, 2014·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·G SamonisM E Falagas
Sep 8, 2010·Expert Review of Anti-infective Therapy·Argyris S Michalopoulos, Dimitra C Karatza
Feb 23, 2013·Expert Review of Anti-infective Therapy·Matthew E FalagasKonstantinos Z Vardakas
Oct 14, 2008·Expert Review of Anti-infective Therapy·Matthew E FalagasArgyris Michalopoulos
Jun 14, 2008·Expert Opinion on Investigational Drugs·Matthew E Falagas, Petros I Rafailidis
May 29, 2012·Médecine et maladies infectieuses·S Mezghani MaalejA Hammami
Jun 18, 2011·The Medical Clinics of North America·Luke F Chen, Donald Kaye
Dec 7, 2010·International Journal of Antimicrobial Agents·Helen Giamarellou
Nov 17, 2009·Infectious Disease Clinics of North America·Luke F Chen, Donald Kaye
Aug 25, 2009·The Journal of Hospital Infection·K J Towner
Jul 15, 2009·The Journal of Hospital Infection·M E Falagas, D E Karageorgopoulos
Nov 22, 2008·The Lancet Infectious Diseases·Drosos E Karageorgopoulos, Matthew E Falagas
Aug 19, 2015·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·D R GiacobbeM Tumbarello
Apr 15, 2014·Transplant Infectious Disease : an Official Journal of the Transplantation Society·M P FreireE Abdala
Jul 19, 2011·Critical Care Research and Practice·Rishi H-P Dhillon, John Clark
May 20, 2015·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·Y-C WangF-Y Chang

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antimicrobial Resistance (ASM)

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Acinetobacter Infections

Acinetobacter infections have become common in hospitalized patients, especially in the intensive care unit setting and are difficult to treat due to their propensity to develop antimicrobial drug resistance. Discover the latest research on Acinetobacter Infections here.

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.