PMID: 9441118Dec 1, 1996Paper

Risk factors for asthma among young adults in Melbourne, Australia

Respirology : Official Journal of the Asian Pacific Society of Respirology
M AbramsonE H Walters

Abstract

Asthma is more prevalent in Australia than in Europe or North America. As part of the European Community Respiratory Health Survey (ECRHS), we investigated exposure to risk factors for asthma among young adults in Melbourne. During this study, 553 randomly selected and 204 symptomatic participants aged between 20 and 44 years completed a detailed respiratory questionnaire, of whom 675 underwent measurement of bronchial hyperreactivity (BHR) by methacholine challenge and 745 had skin prick tests for atopy. Current asthma, defined as BHR and wheeze in the preceding 12 months, was present in 25.5% of those tested. A family history of asthma was a risk factor for current asthma (maternal asthma odds ratio [OR] 2.4, paternal asthma OR 2.1). Current smokers were 1.7 times more likely to have current asthma. A serious respiratory infection before 5 years of age increased the risk of current asthma 2.3-fold. Atopy on skin testing was also strongly associated with current asthma (OR 5.9). The greatest risks were associated with positive skin tests to Cladosporium, house dust mite, cat and rye grass pollen. We conclude that female gender, maternal asthma, smoking, hayfever, early respiratory infection, occupational exposure and atopy are...Continue Reading

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Citations

Apr 23, 1999·American Journal of Industrial Medicine·L FritschiJ McNeil
Apr 25, 2012·Current Allergy and Asthma Reports·Simone AccordiniDeborah Jarvis
Apr 15, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·S DharmageE H Walters
Oct 16, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·S DharmageE H Walters
Oct 7, 2000·Respirology : Official Journal of the Asian Pacific Society of Respirology·R K WoodsM J Abramson
Sep 1, 2007·Journal of Toxicology and Environmental Health. Part a·Charmian M BennettMichael J Abramson
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Mar 13, 2012·Journal of Occupational and Environmental Medicine·Eva SuarthanaEdward L Petsonk
Sep 12, 1998·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·S C DharmageE H Walters
Aug 9, 2011·Archivos de bronconeumología·Roberto Pelta FernándezVerónica Sanz De Burgoa Gómez-Piñán
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Apr 17, 2012·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Aydanur EkiciAli Karlidag
Nov 7, 2016·The Journal of Allergy and Clinical Immunology. in Practice·Eyal OrenAnne L Wright
Sep 20, 2007·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·B ErbasM Abramson
Jul 13, 2005·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M C MathesonE H Walters
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Jul 17, 2010·Journal of Applied Physiology·Mariana A AntunesPatricia R M Rocco
Mar 3, 2009·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Kelly ChuggAlan Crockett
Jul 31, 2020·International Journal of Epidemiology·Jillian IkinMichael J Abramson
Jul 30, 2004·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Federico MontealegreManuel Bayona
Sep 8, 2001·The Medical Journal of Australia·A J WoolcockV A Keena

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