Abstract
We assessed the association of asthma prevalence in young adults with susceptibility factors and environmental exposures, taking into account the age at asthma onset. A random sample of the general population, aged 20-44 yrs, in five areas of Spain (Albacete, Barcelona, Galdakao, Huelva, and Oviedo) was selected in the frame of the European Community Respiratory Health Survey (ECRHS). Overall, 2,646 subjects (response rate = 60.9%) responded to a respiratory questionnaire and 1,797 (41.4%) finalized a bronchial challenge. Atopy to perennial (odds ratio (OR) = 10.2, 95% confidence interval 4.2-25) and seasonal allergens (11.5, 4.6-28), parental asthma (4.5, 2.5-8.4), and birth order (OR for no older siblings in comparison to having more than two = 3.2, 1.2-9.1) were associated with current asthma whatever the age of asthma onset. Past asthma was associated to a lesser extent with atopy (OR around 3.5 to both perennial and seasonal allergens). Lower respiratory tract infections before the age of 5 yrs (LRTI), having had a pet in childhood, and being born in a younger cohort were associated with asthma starting before the age of 15 yrs, but not after. Male gender was more frequent in childhood asthma and female gender in adulthood...Continue Reading
Citations
Oct 16, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M E Hyland
Aug 25, 2001·American Journal of Respiratory and Critical Care Medicine·C D PoirierP Ernst
Jul 22, 2005·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Andrea T BorchersM Eric Gershwin
Nov 23, 2006·European Journal of Epidemiology·Mario GrassiRoberto de Marco
Apr 17, 2007·Cadernos de saúde pública·Silvia Elaine Cardozo MacedoEdgar Fiss
Feb 6, 2010·Allergy·J M AntóP Burney
Jan 8, 2011·Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan·Tomoko SuzukiHitoshi Sato
Apr 23, 2013·Clinical and Experimental Immunology·A-M HughesA-L Ponsonby
Mar 16, 2017·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Souheil HallitPascale Salameh
Aug 12, 2017·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Jaeeun MyungEuna Han
Feb 19, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·E von Mutius
Jan 29, 2000·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M KilpeläinenM Koskenvuo
Aug 2, 2000·Allergy·C SégalaT Lepage
Feb 16, 2006·Pediatric Pulmonology·Anne L WrightFernando D Martinez
Apr 25, 2006·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·P PallasahoB Lundbäck
Apr 11, 2012·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Gabriel Juliá-SerdáJosep Antó-Boqué
Apr 3, 2001·American Journal of Epidemiology·C Infante-RivardJ L Malo
Sep 16, 2000·American Journal of Respiratory and Critical Care Medicine·P P PlaschkeB Järvholm
Aug 3, 2002·Respirology : Official Journal of the Asian Pacific Society of Respirology·Mohammad Hossein Boskabady, Gholam Hassan Kolahdoz
Mar 10, 2011·Journal of Clinical Pharmacy and Therapeutics·H KotaniY Noda
Sep 24, 2009·Allergy·G J BurbachT Zuberbier
Apr 5, 2005·American Journal of Respiratory and Critical Care Medicine·Piush J MandhaneMalcolm R Sears
Dec 10, 2016·Expert Review of Respiratory Medicine·José L Sánchez-RamosFrancisco Gómez-Real
Oct 20, 2001·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·T N WangY C Ko
Oct 5, 2010·American Journal of Respiratory and Critical Care Medicine·Yue ZhangKiros Berhane
Oct 27, 2001·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M E Hyland
Jun 17, 2003·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Kazuhiko SuzukiShosaku Abe
Jan 1, 2011·Multidisciplinary Respiratory Medicine·Francisco J Gonzalez-BarcalaBahi Takkouche
Mar 13, 2008·Indoor Air·C SvanesJ M Antó
Jul 31, 2010·Pediatric Pulmonology·Hanne Vebert OlesenUNKNOWN Scandinavian Cystic Fibrosis Study Consortium
Oct 1, 2008·The Clinical Respiratory Journal·C Svanes
Jun 3, 2021·Allergology International : Official Journal of the Japanese Society of Allergology·Tetsuro FujinoUNKNOWN Japan Environment and Children's Study (JECS) Group