Risk factors for candidemia in a children's hospital

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
L MacDonaldC Chenoweth

Abstract

Candida species are increasingly important nosocomial pathogens in critically ill children. A 2.3-fold increase in the rate of nosocomial candidemia at our 200-bed tertiary care children's hospital prompted a study to identify risk factors for this infection. Twenty-six cases were identified between 1992 and 1993, representing 21% of all nosocomial bloodstream infections. Candida albicans was the most frequent isolate (58%), followed by Candida parapsilosis (27%). A case-control study revealed that there was a statistically significant association between the occurrence of candidemia and placement of a central venous catheter in the femoral vein (P = .03), the use of a tunneled central venous catheter (P = .05), and prolonged hyperalimentation (P = .04). Patients with candidemia also were noted to have candiduria more often than controls (P = .003) and were more likely to have had topical antifungal agents prescribed (P = .04). Multivariate analysis showed that hyperalimentation was an independent risk factor for the development of candidemia. We conclude that measures must be taken to reduce these risk factors whenever possible.

Citations

Sep 4, 2008·Current Infectious Disease Reports·George M Varghese, Jack D Sobel
Nov 30, 2000·Current Infectious Disease Reports·P G Pappas, J H Rex
Nov 30, 2000·Current Infectious Disease Reports·C M Toscano, W R Jarvis
Nov 13, 2009·Indian Journal of Pediatrics·Sunit Singhi, Akash Deep
Jan 25, 2003·Diagnostic Microbiology and Infectious Disease·Suzanne PulimoodPranatharthi Chandrasekar
Nov 1, 2003·The Lancet Infectious Diseases·Philippe EggimannDidier Pittet
Dec 11, 2002·Mycoses·A Nedret KoçZ Gündüz
May 19, 2007·Medical Mycology·Joshua PerlrothBrad Spellberg
Apr 3, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J H Rex, J D Sobel
Jun 22, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J D Sobel, J H Rex
Oct 6, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Theoklis E ZaoutisChris Feudtner
Jul 20, 2010·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Theoklis E ZaoutisRobert Gross
Jul 13, 2004·The Pediatric Infectious Disease Journal·Theoklis E ZaoutisSusan E Coffin
Aug 12, 2005·The Pediatric Infectious Disease Journal·Theoklis E ZaoutisThomas J Walsh
Jun 25, 2004·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Sunit C SinghiArunloke Chakrabarti
Feb 14, 2006·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Josef Ben-AriTommy M Schonfeld
May 15, 2008·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Sunit SinghiArunalok Chakrabarti
Mar 5, 2011·The Pediatric Infectious Disease Journal·Ankhi Dutta, Debra L Palazzi
Dec 18, 2012·The Pediatric Infectious Disease Journal·Clarissa OeserShamez Ladhani
Oct 16, 2008·Clinical Microbiology Reviews·David TrofaJoshua D Nosanchuk
Dec 16, 2011·Journal of Clinical Microbiology·Kaede V Ota, Karin L McGowan
Oct 7, 2005·Journal of Clinical Microbiology·Teresa J StradomskaDanuta Dzierzanowska
Nov 23, 2011·Italian Journal of Pediatrics·Ali Ertug ArslankoyluSemra Erdogan
Aug 28, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Peter G PappasUNKNOWN NIAID Mycoses Study Group
Apr 22, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Richard H DrewJohn R Perfect
Oct 5, 2010·Critical Reviews in Microbiology·Louis Yi Ann ChaiPeter Warn
Jun 2, 2010·Current Medical Research and Opinion·Theoklis Zaoutis
Jan 13, 2000·Journal of Chemotherapy·B J KhooryV Fanos
Jul 26, 2005·Journal of Chemotherapy·G GiusianoV Gómez
Aug 21, 2010·Journal of Medical Microbiology·Teresa J StradomskaDanuta Dzierzanowska
Nov 29, 2014·Indian Journal of Pediatrics·Charu AgrawalBhupendra Singh Chauhan
Nov 10, 2015·Indian Journal of Pathology & Microbiology·Rahul Gopichand Wadile, Viraj Madhusudan Bhate
Sep 29, 2004·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Marie-Elisabeth BougnouxChristophe d'Enfert
Jul 25, 2006·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Jaffar A Al-Tawfiq
Mar 21, 2006·Diagnostic Microbiology and Infectious Disease·Lucía García San MiguelSantiago Moreno
Jun 7, 2006·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Lucia Garcia-San MiguelSantiago Moreno
Oct 12, 2004·Medical Mycology·Victor SilvaUNKNOWN Chilean Invasive Fungal Infections Group
Apr 19, 2005·Medical Mycology·A Brian Mochon, Jim E Cutler
Jul 31, 2004·Medical Mycology·Victor SilvaMaria Christina Diaz
Nov 13, 2018·The Pediatric Infectious Disease Journal·Emmanuel RoilidesUNKNOWN Anidulafungin A8851008 Pediatric Study Group
Dec 22, 2005·Mycoses·Gustavo GiusianoMaría Cristina Díaz

❮ Previous
Next ❯

Related Concepts

Related Feeds

Candidiasis

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Candidiasis (ASM)

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Candida albicans

Candida albicans is an opportunistic, fungal pathogen of humans that frequently causes superficial infections of oral and vaginal mucosal surfaces of debilitated and susceptible individuals. Discover the latest research on Candida albicans here.

Related Papers

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
J K Stamos, A H Rowley
Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America
A Rodríguez-Núñez
Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Sunit C SinghiArunloke Chakrabarti
The Pediatric Infectious Disease Journal
Theoklis E ZaoutisSusan E Coffin
© 2022 Meta ULC. All rights reserved