Risk factors for concurrent bacteremia in adult patients with dengue

Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi
Tun-Linn TheinDavid C Lye

Abstract

Bacteremia in dengue may occur with common exposure to pathogens in association with severe organ impairment or severe dengue, which may result in death. Cohort studies identifying risk factors for concurrent bacteremia among patients with dengue are rare. We conducted a retrospective case-control study of adult patients with dengue who were admitted to the Department of Infectious Diseases at Tan Tock Seng Hospital, Singapore from 2004 to 2008. For each case of dengue with concurrent bacteremia (within the first 72 hours of admission), we selected four controls without bacteremia, who were matched on year of infection and dengue confirmation method. Conditional logistic regression was performed to identify risk factors for concurrent bacteremia. Among 9,553 patients with dengue, 29 (0.3%) had bacteremia. Eighteen of these patients (62.1%) had concurrent bacteremia. The predominant bacteria were Staphylococcus aureus, one of which was a methicillin-resistant strain. Dengue shock syndrome occurred more frequently and hospital stay was longer among cases than among controls. Three cases did not survive, whereas none of the controls died. In multivariate analysis, being critically ill at hospital presentation was independently ass...Continue Reading

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Citations

Dec 3, 2016·Journal of Medical Microbiology·Chin-Ming ChenWen-Liang Yu
Apr 25, 2017·PloS One·Prapit TeparrukkulDirek Limmathurotsakul
Jun 27, 2018·Indian Journal of Ophthalmology·Richa KamalHajib Narahari Rao Madhavan
Dec 27, 2019·PLoS Neglected Tropical Diseases·Chih-Cheng HsiehChia-Chang Chuang
Oct 28, 2016·Expert Review of Anti-infective Therapy·Tau Hong LeeYee Sin Leo
Apr 9, 2020·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Wen-Hung WangSheng-Fan Wang
Apr 23, 2021·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Jen-Chieh LeeWen-Chien Ko
Jul 9, 2021·Drug Discoveries & Therapeutics·Nazneen Nahar BegamAshutosh Biswas
Sep 12, 2021·Journal of Medical Case Reports·Shafiq A AlemadNuha Al-Kufiley
Mar 14, 2020·Infectious Disorders Drug Targets·Durga Shankar MeenaPrakrati Yadav

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