Risk factors for congenital cryptorchidism in a prospective birth cohort study.

PloS One
Ida N DamgaardKatharina M Main

Abstract

Risk factors for congenital cryptorchidism were investigated in a prospective birth cohort study in Denmark and Finland from 1997 to 2001. In total, 2,496 boys were examined for cryptorchidism at birth (cryptorchid/healthy: 128/2,368) and three months old (33/2,215). Information on risk factors was obtained antenatally (questionnaire/interview) or at birth from birth records. Use of nicotine substitutes during pregnancy (n = 40) and infertility treatment by intrauterine insemination (n = 49) were associated with an increased risk for cryptorchidism, adjusted odds ratio (95% confidence interval) (OR (95%CI)) 3.04 (95%CI 1.00-9.27) and 3.01 (95%CI 1.27-7.15), respectively. No association was seen for mothers (n = 79) who had infertility treatment in form of intracytoplasmic sperm injection (ICSI) or in vitro fertilization (IVF) treatment (OR 0.71 95%CI 0.21-2.38). In total, 728 (29%) reported to have smoked during pregnancy, however, no increased risk among maternal smokers was found. Furthermore, we found statistically significant associations between cryptorchidism and low birth weight, prematurity, being small for gestational age, substantial vaginal bleeding, and breech presentation, which are in accordance with other studies...Continue Reading

References

Sep 7, 1978·The New England Journal of Medicine·K J Rothman, C Louik
Feb 1, 1977·The Journal of Urology·M D CoscroveB E Henderson
Jan 1, 1992·The Kurume Medical Journal·M MoriK Fukuda
Dec 1, 1991·International Journal of Epidemiology·M L McBrideR P Gallagher
Dec 1, 1989·Journal of Epidemiology and Community Health·M HjertkvistA Bergh
Jun 1, 1986·International Journal of Epidemiology·T W DaviesR H Whitaker
Sep 1, 1983·Journal of Epidemiology and Community Health·A J SwerdlowP G Smith
Sep 1, 1984·International Journal of Epidemiology·R H Depue
Nov 1, 1984·American Journal of Epidemiology·C M BeardR C Benson
May 1, 1981·American Journal of Epidemiology·C P TorfsB J van den Berg
Mar 1, 1995·Epidemiology·G S BerkowitzI R Holzman
Oct 1, 1993·British Journal of Obstetrics and Gynaecology·J M WelchC Bradbeer
May 3, 1996·International Journal of Cancer. Journal International Du Cancer·H Møller, N E Skakkebaek
Jan 1, 1996·Paediatric and Perinatal Epidemiology·G S Berkowitz, R H Lapinski
Jan 14, 1998·Cancer Causes & Control : CCC·H Møller, N E Skakkebaek
Mar 25, 1999·Environmental Health Perspectives·L J Paulozzi
Jul 13, 1999·Epidemiology·O AkreA Ekbom
Jul 13, 1999·Epidemiology·J B Klotz, L A Pyrch
Jan 21, 2000·Hormone Research·J Toppari, M Kaleva
Mar 3, 2001·Human Reproduction·A Ericson, B Källén
Apr 13, 2001·Teratogenesis, Carcinogenesis, and Mutagenesis·T Nagao, S Yoshimura
Jan 5, 2002·Scandinavian Journal of Public Health·J OlsenC Søndergaard
Feb 26, 2003·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·O C M PereiraD C C Gerardin
Jan 14, 2004·American Journal of Epidemiology·Katrine AlbertsenMorten Grønbaek
Jun 19, 2004·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Sven Cnattingius
Sep 24, 2004·International Journal of Andrology·Ibrahim M Adham, Alexander I Agoulnik
Nov 9, 2004·Environmental Health Perspectives·Frank H PierikRob F A Weber
Apr 20, 2005·Journal international de bioéthique = International journal of bioethics·UNKNOWN World Medical Association General Assembly
Dec 31, 2005·The Journal of Clinical Endocrinology and Metabolism·Robert F Casper, Mohamed F M Mitwally
Jan 6, 2006·Obstetrics and Gynecology·María M Morales-Suárez-VarelaJorn Olsen
Jan 6, 2006·The Journal of Clinical Endocrinology and Metabolism·Anne-Maarit SuomiJorma Toppari
Feb 10, 2006·International Journal of Andrology·Anders Nyboe Andersen, Karin Erb
Apr 6, 2006·Birth Defects Research. Part A, Clinical and Molecular Teratology·Willemijn M MeijerHermien E K de Walle
May 2, 2006·Obstetrics and Gynecology·Peter Davidson

❮ Previous
Next ❯

Citations

Jun 15, 2010·La Presse médicale·Kathy Wagner-MahlerPatrick Fenichel
Aug 27, 2014·Clinics in Perinatology·Lauren BaldingerAseem R Shukla
Jun 18, 2014·Nature Reviews. Endocrinology·Anders JuulNiels E Skakkebæk
Jun 16, 2011·Canadian Urological Association Journal = Journal De L'Association Des Urologues Du Canada·Sophie GuertinStéphane Bolduc
Dec 27, 2013·Asian Journal of Andrology·Linn Berger HåkonsenCecilia Høst Ramlau-Hansen
Apr 14, 2012·Current Opinion in Endocrinology, Diabetes, and Obesity·Helena E VirtanenJorma Toppari
Mar 16, 2011·Nature Reviews. Urology·Katrine BayNiels E Skakkebæk
Feb 16, 2013·Reproductive Toxicology·Laura N VandenbergR Thomas Zoeller
Jun 15, 2011·Molecular and Cellular Endocrinology·Eeva-Maria LaitinenTaneli Raivio
Dec 1, 2010·Journal of Pediatric Urology·Marijn M BrouwersNel Roeleveld
May 19, 2010·The Journal of Urology·Jenny H Yiee, Laurence S Baskin
Oct 20, 2012·Birth Defects Research. Part A, Clinical and Molecular Teratology·Julia Spencer BartholdJeanne M Manson
Dec 14, 2011·International Journal of Andrology·C SplingartF Guérif
Apr 5, 2011·Birth Defects Research. Part A, Clinical and Molecular Teratology·Scott V AdamsJacqueline R Starr
Sep 25, 2010·Birth Defects Research. Part A, Clinical and Molecular Teratology·Jorma ToppariNiels E Skakkebaek
Jan 25, 2014·American Journal of Medical Genetics. Part a·A J AgopianMark A Canfield
Sep 29, 2009·International Journal of Andrology·K Krysiak-BaltynK M Main
Jun 24, 2010·The Urologic Clinics of North America·Richard A AshleyThomas F Kolon
Oct 23, 2015·International Journal of Endocrinology·Marta Diana KomarowskaWojciech Debek
Aug 3, 2010·Early Human Development·Simone FunkeTibor Ertl
Jan 18, 2011·Environmental Health : a Global Access Science Source·María M Morales-Suárez-VarelaJens P Bonde
Aug 8, 2015·Cadernos de saúde pública·Dilvania NicolettiLinjie Zhang
Jun 28, 2017·Nature Reviews. Urology·Jason K GurneyDiana Sarfati
Oct 5, 2017·Revista da Associação Médica Brasileira·Adrianne Maria Berno de Rezende DuarteJosé Murillo de Bastos-Netto
Jun 19, 2018·Epidemiology·Linn Håkonsen ArendtCecilia Høst Ramlau-Hansen
May 15, 2013·The Journal of Urology·Jason GurneyRodney Studd
Mar 27, 2019·BMJ : British Medical Journal·Alexander ChoAbraham Cherian
Mar 12, 2020·The American Journal of Tropical Medicine and Hygiene·Rômulo A L de VasconcelosDemócrito de B Miranda-Filho
Mar 16, 2012·Endocrine Reviews·Laura N VandenbergJohn Peterson Myers
Jun 14, 2016·Birth Defects Research. Part B, Developmental and Reproductive Toxicology·Sonia ChaabaneAnick Bérard
Feb 6, 2020·Frontiers in Endocrinology·Wiwat RodprasertJorma Toppari
Jun 14, 2020·The Journal of Pediatrics·Philip BoehmeKai O Hensel
Mar 5, 2013·Urology·Jeong Kyoon BangSeung-Hun Song
Dec 24, 2014·Pediatrics·Anna R RasmussenKatharina M Main

❮ Previous
Next ❯

Methods Mentioned

BETA
contraception
pregnancy tests
cesarean section

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Related Papers

The Journal of Urology
I S WeidnerNiels E Skakkebaek
The Journal of Clinical Endocrinology and Metabolism
Katharina M MainNiels E Skakkebaek
Birth Defects Research. Part A, Clinical and Molecular Teratology
J S BartholdJeanne M Manson
© 2022 Meta ULC. All rights reserved