Risk factors for deep vein thrombosis after orthopedic surgery and the diagnostic value of D-dimer

Annals of Vascular Surgery
Yong JiangWei-Guo Zhang

Abstract

This study was prospectively designed to determine the risk factors of deep vein thrombosis (DVT) in patients who underwent different surgeries, and to evaluate the efficacy and accuracy of plasma D-dimer level as a screening test. From June 2013 to June 2014, 360 consecutive patients undergoing orthopedic surgery were evaluated. All patients underwent ultrasonography preoperatively and on postoperative day 7. Plasma D-dimer levels were estimated by latex immunoturbidimetry on the day of surgery and on postoperative days 1, 3, and 7. Of the 360 patients in this study, 339 patients completed the analysis. Among them, DVT was confirmed in 28 (8.26%) patients based on ultrasonographic findings. Multivariate logistic analysis revealed that body mass index was an independent risk factor for developing DVT (P = 0.018) and D-dimer levels on postoperative days 1 and 7 were independently correlated with the development of DVT (P = 0.019 and P < 0.001, respectively). The receiver operating characteristic curve analysis determined that the area under the curve was largest (0.752) when using D-dimer level on postoperative day 7 as diagnostic index, and the sensitivity and specificity were 71.4% and 81.7% at the cut-off value of 6.17 μg/mL,...Continue Reading

References

Aug 8, 1986·JAMA : the Journal of the American Medical Association·A E Baue
Aug 8, 1986·JAMA : the Journal of the American Medical Association
Oct 1, 1995·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·N YamadaK Suzuki
Aug 13, 2002·Current Opinion in Pulmonary Medicine·Richard H White, Mark C Henderson
Aug 16, 2002·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Naofumi ShiotaHajime Inoue
Dec 25, 2002·Journal of Orthopaedic Trauma·Luise J HarrisonAllen E Goodship
Jul 23, 2003·Journal of Thrombosis and Haemostasis : JTH·R E G SchutgensD H Biesma
Sep 26, 2003·The New England Journal of Medicine·Philip S WellsMichael J Kovacs
Mar 12, 2004·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·A EliasF Joffre
May 15, 2004·Clinical Chemistry·Steven W HeimJohn T Philbrick
May 24, 2005·Thrombosis Research·Gregor WaserWalter A Wuillemin
Jul 27, 2005·American Journal of Hematology·Satoshi OtaTakeshi Nakano
Sep 6, 2005·The Journal of Bone and Joint Surgery. American Volume·Jay R Lieberman, Wellington K Hsu
Mar 8, 2008·Annals of the Royal College of Surgeons of England·A RafeeG J McLauchlan
Oct 1, 2008·Archives of Orthopaedic and Trauma Surgery·Myung-Chul YooKang-Il Kim
May 27, 2009·British Journal of Haematology·Melanie TanMenno V Huisman
Jan 1, 2012·Annals of Vascular Diseases·Masatoshi MotohashiYoshiro Matsui

❮ Previous
Next ❯

Citations

May 26, 2018·Biomechanics and Modeling in Mechanobiology·Sumith YesudasanRodney D Averett
Aug 9, 2020·Journal of Orthopaedic Surgery and Research·Cheng LiAndrej Trampuz
Apr 14, 2017·World Journal of Gastroenterology : WJG·Masatoshi KochiHideki Ohdan
Sep 22, 2020·Indian Journal of Orthopaedics·Chen FeiKun Zhang
Feb 3, 2021·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Peter PoredosJawed Fareed
Dec 12, 2020·Journal of Orthopaedic Surgery and Research·Linqin Wu, Bo Cheng
Aug 28, 2021·Journal of Clinical Medicine·Anna Jungwirth-WeinbergerFriedrich Boettner
Jan 5, 2022·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Haiying WangShunyi Wang

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.