Risk Factors for Depression: Differential Across Age?

The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry
Roxanne SchaakxsBrenda W J H Penninx

Abstract

The occurrence of well-established risk factors for depression differs across the lifespan. Risk factors may be more strongly associated with depression at ages when occurrence, and therefore expectance, is relatively low ("on-time off-time" hypothesis). This large-scale study examined absolute and relative risks of established risk factors for depression across the lifespan. Participants were 2,215 currently or never depressed adults aged 18 to 93 years from two cohort studies: NESDA and NESDO. The occurrence of 19 established risk factors (absolute risk) was examined in different age groups. In addition, the relative risk of these risk factors for depression was compared across age groups by examining risk factor × age interaction. The occurrence of all risk factors differed significantly across age groups. Although most risk factors had significant associations with depression across the lifespan, for five risk factors the strength of the association was age-dependent. Stronger associations with depression in younger age were found for childhood abuse, pain, higher body mass index (BMI) and number of chronic diseases, whereas low income imposed a stronger risk in older age. Associations with depression were strongest in age ...Continue Reading

Citations

Feb 17, 2018·British Journal of Clinical Pharmacology·Samanta LalicJenni Ilomäki
Sep 2, 2018·Molecular Psychiatry·Martino Belvederi MurriGeorge S Alexopoulos
Sep 30, 2020·International Journal of Environmental Research and Public Health·Wenceslao PeñateCristian Oyanadel
Nov 12, 2020·Social Psychiatry and Psychiatric Epidemiology·Catherine K EttmanSandro Galea
Feb 10, 2021·Journal of Psychiatric and Mental Health Nursing·Fan-Ko SunChu-Yun Lu
Mar 7, 2021·International Journal of Environmental Research and Public Health·Yuhang WuSongbo Hu
Apr 30, 2021·Frontiers in Psychiatry·William H RoughanMiguel E Rentería
Oct 31, 2021·Journal of Food Biochemistry·Masood Sadiq ButtMuhammad Rizwan
Nov 11, 2021·Journal of the American Heart Association·Eric E SmithZahinoor Ismail
Nov 25, 2021·International Journal of Geriatric Psychiatry·Jon BarrenetxeaWoon-Puay Koh

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Pediatrics International : Official Journal of the Japan Pediatric Society
T TanakaT Hara
The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry
Ilse WielaardD Rhebergen
International Psychogeriatrics
Roxanne SchaakxsHannie C Comijs
The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry
Ilse WielaardD Rhebergen
© 2022 Meta ULC. All rights reserved