Risk factors for early mortality and morbidity after pneumonectomy: a reappraisal

The Annals of Thoracic Surgery
Ziad MansourGilbert Massard

Abstract

Pneumonectomy remains a high-risk procedure. Comprehensive patient selection should be based on analysis of proven risk factors. The records of 323 pneumonectomy patients were retrospectively reviewed. Multiple demographic data were collected. End points were operative mortality at 30 and at 90 days, major procedurally related complications, and cardiovascular events. Univariate and multivariate statistical analyses were performed. Smoking habits, chronic obstructive pulmonary disease (COPD) status, induction chemotherapy status, diabetes, and obesity had no statistical influence on short-term outcomes. After right pneumonectomy, 30-day mortality (p = 0.045) and the incidence of bronchopleural fistulas (p = 0.009) were increased. Multivariate analysis for postoperative bronchopleural fistulas discovered that right pneumonectomies are the sole risk factor (p = 0.015). Univariate analysis for postoperative atrial fibrillation showed that male gender, age 70 and older, hypertension, and dyslipidemia are risk factors. Multivariate analysis found no definite risk factor. Patients with coronary artery disease had more postoperative cardiovascular events (p = 0.003). Among patients free of coronary artery disease, COPD led to an incre...Continue Reading

References

Nov 5, 1997·Journal of Cardiothoracic and Vascular Anesthesia·C J JakobsenE B Andresen
Nov 18, 2000·The Annals of Thoracic Surgery·A BernardJ P Favre
Sep 28, 2001·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·G MyrdalE Ståhle
Feb 21, 2002·The European Respiratory Journal·J P van MeerbeeckM L Vos de Wael
Jan 23, 2003·The Annals of Thoracic Surgery·Louis A LanzaVictor F Trastek
Mar 5, 2003·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Christophoros N ForoulisAchilleas G Lioulias
Mar 24, 2004·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Alper TokerGoksel Kalayci
May 14, 2004·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Angel López-EncuentraCarmen Marrón
Feb 1, 2005·The Annals of Thoracic Surgery·Gail E DarlingRobert Ginsberg
Sep 15, 2005·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Ozcan BirimAd J J C Bogers
Nov 22, 2005·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·O BirimA J J C Bogers
Aug 29, 2006·The Journal of Thoracic and Cardiovascular Surgery·Francesco LeoLorenzo Spaggiari
Jun 20, 2013·Circulation. Arrhythmia and Electrophysiology·Jennifer M WrightPeter A Santucci

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Citations

Dec 18, 2013·Interactive Cardiovascular and Thoracic Surgery·Jelena IvanovicAndrew J E Seely
May 21, 2014·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Masatsugu HamajiClaude Deschamps
May 28, 2014·Journal of the American College of Surgeons·Jacob KlapperMark F Berry
Jul 2, 2011·The Annals of Thoracic Surgery·Felix G FernandezDaniel L Miller
Nov 26, 2009·The Annals of Thoracic Surgery·Niels P van der Kaaij, Jolanda Kluin
Jul 27, 2015·Thoracic Surgery Clinics·Shawn S GrothDavid J Sugarbaker
Oct 25, 2014·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Massimo Di MaioGaetano Rocco
Aug 12, 2016·Respirology : Official Journal of the Asian Pacific Society of Respirology·Verónica GiubergiaClaudio Castaños
Nov 3, 2016·Interactive Cardiovascular and Thoracic Surgery·Megan GarnerLeanne Harling
Mar 4, 2014·Asian Cardiovascular & Thoracic Annals·Jeremiah MartinSibu P Saha
Apr 12, 2018·Respirology : Official Journal of the Asian Pacific Society of Respirology·Lonny YarmusDaniel Steinfort
Oct 11, 2014·World Journal of Clinical Oncology·Feras Al-ShahrabaniWolfram T Knoefel
Apr 24, 2014·Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery·Anthony W KimFrank C Detterbeck
May 26, 2018·JAMA : the Journal of the American Medical Association·Emmanuel MartinodEric Vicaut
Oct 12, 2019·Interactive Cardiovascular and Thoracic Surgery·Igor Ya MotusAnna S Tsvirenko
Apr 8, 2020·Acta chirurgica Belgica·Mustafa Vedat DogruMuzaffer Metin
Jun 15, 2021·Expert Review of Anticancer Therapy·Helene GoussaultChristos Chouaïd
Jul 22, 2021·Seminars in Thoracic and Cardiovascular Surgery·Jeonghee YunYoung Mog Shim

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