PMID: 8580656Oct 1, 1995Paper

Risk factors for ectopic pregnancy after in vitro fertilization and embryo transfer

Journal of Assisted Reproduction and Genetics
M Ribic-PuceljH Meden-Vrtovec

Abstract

To find the incidence of ectopic pregnancy (EP) in patients who conceived in the IVF-ET program, and risk factors affecting the occurrence of EP. We analyzed the effects of the indication for IVF, type of ovarian stimulation (hMG + hCG vs. GnRH + hMG + hCG), type of embryo transfer (transcervical intratubal, intrauterine in chest-knee position and intrauterine in lithotomy position) and number of embryos transferred on the occurrence of EP. EP was treated by laparotomy, prostaglandin E2 or laparoscopic surgery. In 7991 stimulated and 92 natural cycles treated in the Ljubljana IVF-ET program between May 1983 and June 1994 we achieved 1059 pregnancies, of which 44 were ectopic (incidence 4.1%), the main risk being tubal factor infertility. There were 38 (86.3%) tubal, 3 (6.8%) heterotopic, 1 (2.4%) ovarian, and 2 (4.5%) cornual EP. In two patients multiple tubal EP occurred (1 twin, 1 triplet). Forty-two patients (95.4%) had tubal factor infertility, 1 (2.3%) unexplained, and 1 (2.3%) patient had male factor. The incidence of EP in patients with tubal infertility was 5.4%, in patients with unexplained infertility 2.0% and in those with male factor 0.9%. There appeared to be no correlation between the two superovulatory methods. W...Continue Reading

References

Apr 24, 1976·Lancet·P C Steptoe, R G Edwards
Jun 1, 1990·Fertility and Sterility·J B DubuissonL Mandelbrot
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Citations

Apr 13, 2002·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Renato BaumanAsim Kurjak
Dec 23, 1998·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·R G BuckleyJ H Klausen
Jan 7, 2015·Obstetrics and Gynecology·Kiran M PerkinsUNKNOWN National ART Surveillance (NASS) Group
Mar 2, 2006·Obstetrics and Gynecology·Heather B ClaytonVictoria C Wright
Jun 1, 2006·Animal Genetics·Y MoodleyE H Harley
Jul 15, 2000·Animal Genetics·L R RitzC Gaillard
Jun 20, 1998·Molecular Ecology·F X VillablancaS R Palumbi

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