Risk factors for end stage renal disease in children with posterior urethral valves

The Journal of Urology
William DeFoorCurtis Sheldon

Abstract

Obstructive uropathy secondary to posterior urethral valves is an important cause of end stage renal disease in children. Early diagnosis and intervention to decrease bladder pressure and stabilize the upper urinary tract are important to delay or prevent the progression of renal insufficiency. We analyzed the records of patients with posterior urethral valves to determine risk factors that might be predictive of ultimate renal failure. A retrospective cohort study was performed of children presenting to our institution with a diagnosis of posterior urethral valves from 1975 to 2005. Patient demographics, clinical background, laboratory and radiographic data, and renal outcomes were abstracted from the medical record. Potential risk factors were analyzed, such as high grade vesicoureteral reflux at diagnosis, nadir serum creatinine greater than 1.0 mg/dl, urinary tract infection and severe bladder dysfunction requiring clean intermittent catheterization. Risk factors were analyzed by univariate analysis with Fisher's exact test. Those achieving significance were placed in a multivariate logistic regression model and an OR was generated. A total of 142 patients were identified, of whom half presented in the neonatal period. Of t...Continue Reading

References

Nov 12, 1998·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·D DrozdzK Schärer
Apr 11, 2001·Pediatric Surgery International·M BajpaiD K Gupta
Dec 18, 2001·The Journal of Urology·Stephen A KoffVenkata R Jayanthi
Nov 25, 2003·The Journal of Urology·William DeFoorCurtis Sheldon
Jun 5, 2004·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Elisa YlinenSakari Wikström
Sep 8, 2005·The Journal of Urology·K L NarasimhanA Bhattacharya

❮ Previous
Next ❯

Citations

Feb 18, 2011·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Susan E Ingraham, Kirk M McHugh
Oct 11, 2012·International Journal of Nephrology·Odutola Israel OdetundeNene Elsie Obianyo
Mar 4, 2011·Indian Journal of Urology : IJU : Journal of the Urological Society of India·Joseph Thomas
Apr 1, 2014·The Journal of Urology·Nathan A HoagKourosh Afshar
Dec 19, 2012·The Journal of Urology·William R DeFoor
Jan 29, 2013·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·O AbboP Galinier
Nov 29, 2011·The Urologic Clinics of North America·Terry W Hensle, Christopher M Deibert
Oct 22, 2011·The Journal of Urology·Jukka HeikkiläSeppo Taskinen
Sep 8, 2011·Advances in Chronic Kidney Disease·Frank J Penna, Jack S Elder
May 13, 2011·The Journal of Urology·Osama M SarhanEl-Houssiny I Ibrahiem
Mar 17, 2011·The American Journal of Emergency Medicine·Joshua Schecter, Jennifer H Chao
Sep 11, 2010·Journal of Pediatric Urology·Yusuf KibarBradley P Kropp
Aug 22, 2015·Journal of Pediatric Urology·R ColemanK Parashar
Jan 22, 2013·Journal of Paediatrics and Child Health·Henrietta U OkaforSamuel N Uwaezuoke
Mar 2, 2016·The Journal of Urology·Katherine FischerGregory E Tasian
May 27, 2014·Journal of Pediatric Urology·Hahn-Ey LeeHwang Choi
May 22, 2016·Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'obstétrique Et Gynécologie Du Canada : JOGC·Venu JainDarcie A Kiddoo
Apr 17, 2012·Journal of Pediatric Urology·Lei ChuFrancis X Schneck
Jun 18, 2016·The Journal of Urology·W Robert DeFoor
Oct 14, 2016·Seminars in Fetal & Neonatal Medicine·Jason Misurac
Nov 22, 2017·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Aniruddh V Deshpande
May 19, 2018·Current Urology Reports·Christopher J Long, Diana K Bowen
Mar 19, 2013·British Journal of Hospital Medicine·Osasuyi IyasereKevin Harris
Dec 7, 2013·Clinical Journal of the American Society of Nephrology : CJASN·Jose E PulidoGregory E Tasian
Nov 14, 2012·Nature Reviews. Urology·Seppo TaskinenRisto Rintala
Sep 1, 2019·Journal of Perinatology : Official Journal of the California Perinatal Association·Madeline CoquilletteDeborah R Stein
Jul 20, 2019·American Journal of Physiology. Renal Physiology·Ashley R JacksonBrian Becknell
Feb 24, 2017·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Érica Leandro Marciano VieiraAna Cristina Simões E Silva
Feb 25, 2017·Current Urology Reports·Charles W ConcodoraBrian A VanderBrink
Sep 10, 2018·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Mariana A VasconcelosEduardo A Oliveira
Oct 31, 2021·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Charlotte Q WuEdwin A Smith
Feb 3, 2019·Pediatrics·Daryl J McLeodUNKNOWN Pediatric Urology Midwest Alliance (PUMA)

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bladder Carcinoma In Situ

Bladder Carcinoma In Situ is a superficial bladder cancer that occurs on the surface layer of the bladder. Discover the latest research on this precancerous condition in this feed.