Risk Factors for Failure of Systemic-to-Pulmonary Artery Shunts in Biventricular Circulation

Pediatric Cardiology
Keti VitanovaJulie Cleuziou

Abstract

Systemic-to-pulmonary artery shunt placement is an established palliative procedure for congenital heart disease, but it is associated with high morbidity and mortality. Data of all patients with biventricular circulation who underwent systemic-to-pulmonary artery shunt implantation between 2000 and 2016 were reviewed. Endpoints of the study were shunt failure and shunt-related mortality. Shunt failure was defined as any shunt dysfunction requiring intervention or reoperation. Shunt-related mortality was defined as death due to shunt dysfunction. A total of 217 shunts (central shunt, n = 131, Blalock-Taussig shunt, n = 86) were implanted in 178 patients. The median age of the patients was 98 days [1 day to 1.2 years]. Corrective surgery was performed at a median time of 0.6 years [3 months to 7 years] after shunt placement. Shunt failure was diagnosed in 21 patients (9.6%) at a median time of 14.6 days [0 days to 2 years]. Causes of shunt failure were stenosis (n = 11; 5%) and thrombosis (n = 10; 4.6%). The rate of freedom from shunt failure was 89.9 ± 2.6% at 1 year, the rate of shunt-related mortality was 3% (n = 5), and the rate of freedom from shunt-related mortality at 1 year was 97.5 ± 1%. Platelet transfusion was require...Continue Reading

References

May 1, 1990·The Annals of Thoracic Surgery·D TamisierJ Y Neveux
Nov 1, 1995·Circulation·J OdimR A Jonas
Jan 1, 1993·Journal of Cardiac Surgery·J P GoldM S Snyder
Jul 1, 1997·The Journal of Thoracic and Cardiovascular Surgery·G GladmanL N Benson
Jul 6, 2000·The Annals of Thoracic Surgery·A M AlkhulaifiC Planché
Apr 10, 2007·Journal of Cardiothoracic and Vascular Anesthesia·Tapan Kumar SahooUsha Kiran
Nov 27, 2007·The Annals of Thoracic Surgery·Jason A WilliamsDuke E Cameron
May 10, 2011·The Annals of Thoracic Surgery·Orlando PetrucciPirooz Eghtesady
Feb 19, 2013·Journal of the American College of Surgeons·E Dean McKenzieCharles D Fraser
Mar 14, 2013·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Claudia ArenzViktor Hraska
Mar 30, 2013·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Verena DirksHitendu Dave
Feb 1, 2014·The Annals of Thoracic Surgery·Naruhito WatanabeFrank L Hanley
Jun 25, 2014·World Journal for Pediatric & Congenital Heart Surgery·Jürgen HörerMatthias Sigler
Dec 31, 2014·World Journal for Pediatric & Congenital Heart Surgery·Thierry BoveKatrien François

❮ Previous
Next ❯

Citations

Mar 14, 2020·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Sirisha EmaniSitaram M Emani

❮ Previous
Next ❯

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.