Risk factors for intraoperative portal vein thrombosis in pediatric living donor liver transplantation

Clinical Transplantation
Yu-Fan ChengBruno Jawan

Abstract

Pathologic changes of the recipient native portal venous system may cause thrombosis of the portal vein, especially in pediatric living donor liver transplantation (LDLT). This study assessed the utility of Doppler ultrasound (US) for the detection of intraoperative portal vein occlusion and identification of predisposing risk factors in the recipients. Seventy-three pediatric recipients who underwent LDLT at Chang Gung Memorial Hospital, Taiwan, from 1994 to 2002 were included. Preoperative and intraoperative Doppler US evaluation of the portal vein was performed. Age, body weight, native liver disease, type of graft, graft recipient weight ratio (GRWR), type of portal anastomosis, portal velocity, portal venous size and presence of portosystemic shunt were analyzed for statistical significance of predisposing risk factors. Eight episodes of intraoperative portal vein thrombosis, with typical findings of absent Doppler flow in portal vein and prominent hepatic artery with a resistant index lower than 0.5 (p < 0.001), were detected during transplantation, which was then corrected by thrombectomy and re-anastomosis. Children age < or =1 yr (p = 0.025), weight < or =10 kg (p = 0.024), low portal flow < or =7 cm/s (p = 0.021), por...Continue Reading

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Citations

May 13, 2008·Journal of Clinical Gastroenterology·Ibrahim ErtuğrulNurgül Saşmaz
Dec 10, 2014·Journal of Pediatric Surgery·Patrick Ho Yu ChungChung Mau Lo
Aug 10, 2010·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·B DresskeD C Bröring
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Mar 9, 2011·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Raymund R RazonableMichael Gropper
Mar 28, 2012·Transplant International : Official Journal of the European Society for Organ Transplantation·Ting-Lung LinChih-Chi Wang
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Apr 27, 2018·Pediatric Transplantation·Lihong GuQiang Xia
Aug 1, 2007·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Joao Seda NetoPaulo Chapchap
Mar 9, 2010·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Yukihiro SanadaHideo Kawarasaki
Jun 26, 2015·World Journal of Gastroenterology : WJG·Sheng-Chun YangKwok-Wai Cheng
Jun 13, 2017·Pediatric Transplantation·Koichiro YoshimaruTomoaki Taguchi
Nov 15, 2020·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Yuktansh PandeySubhash Gupta
Oct 30, 2020·Journal of Clinical Medicine·Suk Kyun HongKyung-Suk Suh

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