Risk factors for late HIV diagnosis in the East of England: evidence from national surveillance data and policy implications

International Journal of STD & AIDS
Rachel E BathMark Reacher

Abstract

In 2014, 42% of all HIV diagnoses in the East of England were diagnosed late. Individuals unaware of their HIV status will not benefit from lifesaving and infectious-limiting antiretroviral therapy, and they remain at risk of decreased life expectancy and onward transmission of HIV. We sought to identify risk factors associated with late HIV diagnosis in the East of England to inform future HIV testing and prevention strategies relevant to the local population. Data on all HIV infected individuals aged ≥16 years and diagnosed between 2008 and 2014 in the East of England were obtained from the national HIV and AIDS Reporting System. Late diagnosis was defined as CD4 cell count below 350 cells/mm3 within 91 days of diagnosis. Logistic regression investigated risk factors for late HIV diagnosis. A total of 2469 people were included; 1342 (54%) were late HIV diagnoses. In multivariable analysis risk factors for late diagnosis were: age ≥30 years, originating from WHO regions of South-East Asia or Europe (excluding UK), heterosexual orientation and being diagnosed as an inpatient or by a general practitioner. The odds of late diagnosis significantly reduced every year (OR 0.95, 95% CI 0.90-0.99, p = 0.042). Despite this year-on-year...Continue Reading

References

Feb 4, 2010·European Journal of Public Health·Jessika DeblondeMarleen Temmerman
Jun 22, 2010·HIV Medicine·A AntinoriUNKNOWN European Late Presenter Consensus Working Group
Nov 10, 2011·Scandinavian Journal of Infectious Diseases·Marie HellebergNiels Obel
Aug 20, 2016·International Journal of STD & AIDS·Dara Spatz FriedmanMarie Roy
Nov 4, 2017·The Lancet. HIV· The Lancet Hiv
Dec 19, 2017·The Lancet. Public Health·Margaret T May

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Citations

Jun 18, 2019·The Cochrane Database of Systematic Reviews·Alberto Mateo-UrdialesIngrid Eshun-Wilson
Jan 24, 2020·International Journal of STD & AIDS·J Horsley DownieD R Chadwick
Jun 4, 2021·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Machiko OtaniUNKNOWN Japanese Drug Resistance HIV-1 Surveillance Network
Oct 2, 2021·AIDS Education and Prevention : Official Publication of the International Society for AIDS Education·Thu Trang NguyenMinh Giang Le

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