Risk factors for levofloxacin-nonsusceptible Streptococcus pneumoniae in community-acquired pneumococcal pneumonia: a nested case-control study

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
C-I KangANSORP Study Group

Abstract

This study was performed to evaluate the clinical features of community-onset levofloxacin-nonsusceptible pneumococcal pneumonia and to identify risk factors for levofloxacin resistance. Using the database of a surveillance study of community-acquired pneumococcal infections in Asian countries, we conducted a nested case-control study to identify risk factors for levofloxacin-nonsusceptible S. pneumoniae in community-acquired pneumonia in adults. Of 981 patients with pneumococcal pneumonia, 46 (4.7 %) had levofloxacin-nonsusceptible S. pneumoniae, of whom 39 evaluable cases were included in the analysis. All cases were from Korea, Taiwan, and Hong Kong. Among patients with levofloxacin-susceptible S. pneumoniae, 490 controls were selected based on patient country. Of the 39 cases of levofloxacin-nonsusceptible pneumococcal pneumonia, 23 (59.0 %) were classified as healthcare-associated, while 164 (33.5 %) of the 490 controls of levofloxacin-susceptible S. pneumoniae (P = 0.001) were classified as healthcare-associated. Multivariate analysis showed that previous treatment with fluoroquinolones, cerebrovascular disease, and healthcare-associated infection were significantly associated with levofloxacin-nonsusceptible pneumococcal...Continue Reading

References

Mar 7, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·P L HoR M Chan
May 6, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·George M Eliopoulos
May 6, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Donald E Low
May 25, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jae-Hoon SongAsian Network for Surveillance of Resistant Pathogens Study Group
Mar 8, 2005·Journal of Clinical Microbiology·M Raquel Marín JiménezJosé Angel García Rodríguez
Dec 29, 2007·International Journal of Antimicrobial Agents·Jae-Hoon SongAsian Network for Surveillance of Resistant Pathogens Study Group
Jul 1, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Marin H KollefJohn Segreti
Dec 3, 2010·The Journal of Antimicrobial Chemotherapy·Willize E van der StarreJaap T van Dissel
Mar 9, 2011·Antimicrobial Agents and Chemotherapy·Iciar Rodríguez-AvialMadrid Streptococcus pneumoniae Microbiological Group
Jul 24, 2012·Infection·C-I KangAsian Network for Surveillance of Resistant Pathogens (ANSORP) Study Group

Citations

Apr 17, 2016·Diagnostic Microbiology and Infectious Disease·Jin Yang BaekANSORP Study Group
Aug 1, 2015·Journal of Basic and Clinical Pharmacy·Soma SarkarManideepa SenGupta
Aug 9, 2016·Diagnostic Microbiology and Infectious Disease·Tark KimYang Soo Kim
May 13, 2017·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Xiaoxia Li, Kyung Ho Row
Mar 23, 2018·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Hyeri SeokKyong Ran Peck
Jan 8, 2015·Infection & chemotherapy·Eu Suk Kim, David C Hooper
Feb 24, 2016·Current Opinion in Pulmonary Medicine·Catia CillónizAntoni Torres

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