Risk factors for local recurrence of middle and lower rectal carcinoma after curative resection.

World Journal of Gastroenterology : WJG
Ze-Yu WuHua-Huan Lin

Abstract

To explore the risk factors for local recurrence of middle and lower rectal carcinoma after curative resection. Specimens of middle and lower rectal carcinoma from 56 patients who received curative resection at the Department of General Surgery of Guangdong Provincial People's Hospital were studied. A large slice technique was used to detect mesorectal metastasis and evaluate circumferential resection margin status. The relations between clinicopathologic characteristics, mesorectal metastasis and circumferential resection margin status were identified in patients with local recurrence of middle and lower rectal carcinoma. Local recurrence of middle and lower rectal carcinoma after curative resection occurred in 7 of the 56 patients (12.5%), and was significantly associated with family history (c2=3.929, P=0.047), high CEA level (c2=4.964, P=0.026), cancerous perforation (c2=8.503, P=0.004), tumor differentiation (c2=9.315, P=0.009) and vessel cancerous emboli (c2=11.879, P=0.001). In contrast, no significant correlation was found between local recurrence of rectal carcinoma and other variables such as age (c2=0.506, P=0.477), gender (c2=0.102, c2=0.749), tumor diameter (c2=0.421, P=0.516), tumor infiltration (c2=5.052, P=0.168...Continue Reading

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Citations

Dec 15, 2011·Cardiovascular and Interventional Radiology·Sophia MylonaLoukas Thanos
Feb 13, 2010·World Journal of Surgery·Yik-Hong HoRussel Stitz
Oct 15, 2013·Journal of Surgical Oncology·Heather L Yeo, Philip B Paty
Jan 30, 2014·Arquivos De Gastroenterologia·Herminio Cabral de Rezende JuniorJaques Waisberg
Nov 27, 2014·European Journal of Gastroenterology & Hepatology·Xing-mao ZhangZhi-xiang Zhou
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Apr 17, 2012·Expert Review of Anticancer Therapy·Georg F WeberHelmut Friess
Aug 16, 2019·Der Radiologe·I Iesalnieks, A Agha

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