Risk Factors for Major Early Adverse Events Related to Cardiac Catheterization in Children and Young Adults With Pulmonary Hypertension: An Analysis of Data From the IMPACT (Improving Adult and Congenital Treatment) Registry

Journal of the American Heart Association
Michael L O'ByrneAndrew C Glatz

Abstract

Cardiac catheterization is the gold standard for assessment and follow-up of patients with pulmonary hypertension (PH). To date, there are limited data about the factors that influence the risk of catastrophic adverse events after catheterization in this population. A retrospective multicenter cohort study was performed to measure risk of catastrophic adverse outcomes after catheterization in children and young adults with PH and identify risk factors for these outcomes. All catheterizations in children and young adults, aged 0 to 21 years, with PH at hospitals submitting data to the IMPACT (Improving Adult and Congenital Treatment) registry between January 1, 2011, and December 31, 2015, were studied. Using mixed-effects multivariable regression, we assessed the association between prespecified subject-, procedure-, and center-level covariates and the risk of death, cardiac arrest, or mechanical circulatory support during or after cardiac catheterization. A total of 8111 procedures performed in 7729 subjects at 77 centers were studied. The observed risk of the composite outcome was 1.4%, and the risk of death before discharge was 5.2%. Catheterization in prematurely born neonates and nonpremature infants was associated with in...Continue Reading

References

Apr 3, 2007·British Journal of Anaesthesia·C J TaylorM R J Sury
Mar 17, 2010·Archives of Cardiovascular Diseases·Alain FraisseDamien Bonnet
Jun 16, 2010·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Kevin D HillJ Donald Moore
Mar 10, 2011·Circulation. Cardiovascular Interventions·Lisa BergersenKathy Jenkins
Sep 24, 2011·JACC. Cardiovascular Interventions·Lisa BergersenKathy J Jenkins
Jan 24, 2012·The Journal of Thoracic and Cardiovascular Surgery·Sara K PasqualiJeffrey P Jacobs
Jan 25, 2012·Pediatrics·Sara K PasqualiJeffrey P Jacobs
Sep 25, 2012·Journal of the American College of Cardiology·John C MessengerUNKNOWN NCDR Science and Quality Oversight Committee Data Quality Workgroup
Apr 9, 2013·The European Respiratory Journal·Maurice BeghettiUNKNOWN TOPP Registry Investigators
Feb 26, 2014·Pediatrics·Sara K PasqualiJennifer S Li
Sep 27, 2014·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Carl H BackesRalf J Holzer
Dec 17, 2014·Journal of the American College of Cardiology·John W MooreUNKNOWN NCDR IMPACT Steering Committee
Jan 13, 2015·Pediatric Cardiology·Prashant BobhateIan Adatia
Sep 12, 2015·Journal of the American College of Cardiology·Jacqueline Kreutzer
Nov 4, 2015·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·David G NykanenUNKNOWN Congenital Cardiac Interventional Study Consortium (CCISC)
Nov 5, 2015·Circulation·Steven H AbmanUNKNOWN American Heart Association Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation; Council on Clinical C
Mar 19, 2016·Journal of the American College of Cardiology·Johannes M DouwesUNKNOWN TOPP Investigators

❮ Previous
Next ❯

Citations

Mar 2, 2018·Journal of the American Heart Association·Anudeep JassalElisa A Bradley
Dec 14, 2018·The European Respiratory Journal·Erika B RosenzweigRolf M F Berger
Jul 28, 2020·The Journal of Pediatrics·Jenny Y ChenAllen D Everett

❮ Previous
Next ❯

Methods Mentioned

BETA
pharmacotherapy

Software Mentioned

SAS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.