PMID: 19122921Jan 6, 2009Paper

Risk factors for mortality in patients with Acinetobacter baumannii bloodstream infection with genotypic species identification

Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi
Dung-Hung ChiangCheng-Yi Liu

Abstract

Acinetobacter baumannii is an increasingly common nosocomial infection with a high mortality rate. Identification of predictor factors of mortality from A. baumannii infection is important for the implementation of therapeutic management for patients with higher risk. However, many studies have reported data for Acinetobacter calcoaceticus-A. baumannii complex, which might lead to an uncertainty of results. In this study, we aimed to identify the predictive factors for mortality of patients infected with true A. baumannii that had been precisely identified by genotypic methodology. Sixty seven patients with documented A. baumannii bacteremia were identified from a medical center in northern Taiwan during the period between February 1998 and February 2001. The patients' medical records were retrospectively reviewed. The risk factors associated with mortality in patients with A. baumannii bacteremia were underlying disease with malignancy, end-stage renal disease, and inappropriate antibiotic therapy. Laboratory variables, such as creatinine level, were also associated with poor prognosis by multivariate analysis. Increased serum creatinine level, malignancy and inappropriate therapy within 3 days were related to increased mortal...Continue Reading

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