Risk factors for non-curative resection of early gastric neoplasms with endoscopic submucosal dissection: Analysis of 1,123 lesions

Experimental and Therapeutic Medicine
Tatsuya ToyokawaJun Tomoda

Abstract

Although the frequency of residual disease and recurrence following endoscopic submucosal dissection (ESD) has markedly decreased, a few cases of residual disease and recurrence following ESD are still observed. The aims of the present study were to clarify the causes of non-curative resection and to investigate the risk factors. A total of 1,123 early gastric neoplasm lesions treated by ESD were investigated. Non-curative resection was defined as histological positivity of the resected margins, vascular invasion or failure of en bloc resection. Cases of non-curative resection were classified as being caused by one of three reasons: Inadequate technique, pre-procedural misdiagnosis or problems in the histological diagnosis. Following classification, the cases of non-curative and curative resection were compared based on a range of patient characteristics: Procedure time, and size, type and location of the lesions. The frequency of non-curative resection was 16% (182 lesions). Non-curative resection occurred due to inadequate technique in 59 cases, pre-procedural misdiagnosis in 88 cases and problems in the histological diagnosis in 35 cases. Multivariate analysis revealed that a large lesion size, long procedure time and inexpe...Continue Reading

References

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Nov 11, 2006·Journal of Gastroenterology·Takuji GotodaRoy M Soetikno
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Dec 7, 2010·European Journal of Clinical Investigation·Tatsuya ToyokawaJun Tomoda
Feb 18, 2011·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Satoru NonakaTakuji Gotoda
May 17, 2011·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·UNKNOWN Japanese Gastric Cancer Association
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Oct 22, 2011·Gastrointestinal Endoscopy·Kingo HirasawaKatsuaki Tanaka

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Citations

Oct 28, 2019·Clinical Endoscopy·Si Hyung LeeUNKNOWN Korean Society of Gastrointestinal Endoscopy Endoscopic Submucosal Dissection Research Group
Sep 10, 2020·Endoscopy International Open·Michele Oliveira De MarcoEduardo Guimarães Hourneaux de Moura
Sep 22, 2017·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Shin Hee Kim, Su Jin Hong

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Methods Mentioned

BETA
dissection

Software Mentioned

SPSS
SPPS

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