Risk factors for pediatric invasive pneumococcal disease in the Intermountain West, 1996-2002

Annals of Epidemiology
Maryam B HaddadCarrie L Byington

Abstract

In response to concerns that the epidemiology of pediatric invasive pneumococcal disease (IPD) in the Intermountain West (i.e., Utah, Idaho, Wyoming, Montana, and parts of Arizona and Nevada) was poorly understood and might differ from elsewhere in the United States, a case-control study was undertaken to determine factors associated with IPD during 1996-2002. A telephone questionnaire was administered to parents of children comprising 120 cases identified through hospital records and to parents of 156 age-matched controls located by random-digit dialing. The unit of analysis was each matched case-control set. Underlying chronic illness was reported for 32 (27%) of the cases. For previously healthy children, breastfeeding had a protective benefit (adjusted odds ratio: 0.2; 95% confidence interval [CI], 0.1-0.6), while a history of tympanostomy tube surgery was a risk factor (adjusted odds ratio: 12.6; 95% CI, 1.5-107.3). The presence of an underlying chronic illness was the strongest risk factor for IPD. Except for a history of tympanostomy tube surgery, the factors associated with IPD in this investigation were similar to those reported from other geographic regions. Tympanostomy surgery might serve as a surrogate indicator fo...Continue Reading

References

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Citations

Apr 19, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jeffrey M BenderCarrie L Byington
Oct 19, 2011·The Pediatric Infectious Disease Journal·Krow AmpofoCarrie L Byington
Apr 23, 2011·Medicine·Thomas James MarrieOtto G Vanderkooi
Apr 27, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Chris StockmannAndrew T Pavia
Jul 23, 2013·International Journal of Clinical Practice·M A RoseI de Schutter
Mar 12, 2017·Environmental Health : a Global Access Science Source·Lisa G GallagherAnn Aschengrau

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