Risk Factors for Physical Disability in Patients With Leprosy: A Systematic Review and Meta-analysis.

JAMA Dermatology
Hidyanara L de PaulaVictor S Santos

Abstract

The World Health Organization (WHO) 2016-2020 Global Leprosy Strategy aims to reinvigorate efforts to control leprosy and avert leprosy disability to less than 1 per million population. To systematically identify clinical factors associated with physical disability in patients with leprosy. Searches were conducted in Scopus, PubMed, and Web of Science databases to identify studies published from January 23, 1988, to May 23, 2018, using the keywords leprosy and physical disability and related terms. Studies that evaluated patients using the WHO leprosy disability grading system and reported the number of patients with and without disability by clinical characteristics were included. The odds ratio (OR) was used as a measure of association between the clinical features and physical disability. Summary estimates were calculated using random-effects models. The primary outcome was physical disability according to the WHO disability classification. The association between clinical features and physical disability was evaluated. The search identified 2447 reports. After screening titles and abstracts, 177 full-text articles were assessed for eligibility, and 32 studies were included in the systematic review; 24 of the 32 studies incl...Continue Reading

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Citations

Mar 7, 2020·The Indian Journal of Medical Research·Kabir Sardana, Ananta Khurana
Apr 23, 2021·Revista brasileira de enfermagem·Luana Karen Dos Santos AmaralGustavo Christofoletti
May 31, 2021·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Rodrigo Feliciano do CarmoCarlos Dornels Freire de Souza
Aug 26, 2021·PLoS Neglected Tropical Diseases·Rachel Bertolani do Espírito SantoPatrícia Deps
Feb 9, 2020·Annales de dermatologie et de vénéréologie·S Ingen-Housz-Oro

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