Risk factors for pneumococcal disease in human immunodeficiency virus-infected patients

The Journal of Infectious Diseases
Kelly A GeboR E Chaisson

Abstract

To identify risk factors for pneumococcal infection among human immunodeficiency virus-infected patients, a nested case-control study was done in an urban university human immunodeficiency virus clinic. Subjects with pneumococcal illness seen between 1 January 1990 and 1 July 1994 (n=85) were randomly matched to controls from the same population. Patients with pneumococcal disease were more likely than controls to be African Americans (adjusted odds ratio [OR]=3.92), have <200 CD4 cells/mm3 (adjusted OR=3.38), have a history of any pneumonia (adjusted OR=3.28), and have an albumin level of <3.0 g/dL (adjusted OR=6.25). Use of zidovudine (adjusted OR=0.38) and pneumococcal vaccination when the subject had >200 CD4 cells/mm3 (adjusted OR=0.22) were less common in cases than in controls. Similar results were found when only cases with infections of usually sterile sites were analyzed. Pneumococcal vaccine may be most protective when it is administered before advanced immunodeficiency develops.

Citations

Sep 22, 2007·Current HIV/AIDS Reports·Edgar Turner Overton
Nov 30, 2000·Current Infectious Disease Reports·S A Tasker, M R Wallace
Mar 10, 2006·Current Infectious Disease Reports·Todd D GleesonSybil A Tasker
Apr 17, 2001·Infectious Disease Clinics of North America·G A Poland
Sep 21, 2001·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·A B Pierce, J F Hoy
Mar 14, 2003·The Journal of Infection·Neil French
Aug 6, 2000·The New England Journal of Medicine·C A Fleming, D E Craven
Nov 30, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·F Castelli, A Patroni
Aug 7, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·C G WhitneyJ C Butler
Jul 29, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Maria C Rodriguez-BarradasJohn Thornby
Jun 8, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Rakhi KohliUNKNOWN HER Study Group
May 1, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Maria C Rodriguez-BarradasAmy C Justice
Aug 1, 1997·AIDS Patient Care and STDs·T L Katzenstein
Apr 7, 2007·AIDS·David R Chadwick, Anna Maria Geretti
Nov 21, 2007·AIDS·Philippe LespritUNKNOWN ANRS 114-Pneumovac Study Group
Jul 2, 2002·Infectious Diseases in Obstetrics and Gynecology·UNKNOWN US Public Health Service, Infectious Diseases Society of America, Prevention of Opportunistic Infections Working Group
Mar 20, 2001·American Journal of Respiratory and Critical Care Medicine·J H SullivanM C Steinhoff
Oct 25, 2007·BMC Infectious Diseases·Maria Amelia S M VerasArthur L Reingold
Feb 19, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Sybil A TaskerEdward N Janoff
Sep 7, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Maria PeñarandaMelcior Riera
Oct 5, 2010·Vaccine·Nancy F Crum-CianfloneUNKNOWN Infectious Disease Clinical Research Program HIV Working Group
Mar 8, 2016·Virulence·Lucia TaramassoAntonio Di Biagio
Nov 3, 2007·The Lancet Infectious Diseases·Sandra J BlissOrin S Levine
Jun 29, 2004·The Lancet Infectious Diseases·Daniel R FeikinEdward N Janoff
Oct 11, 2005·HIV Clinical Trials·Vijayalakshmi Nagappan, Powel Kazanjian
Dec 14, 2001·HIV Clinical Trials·UNKNOWN US Public Health Service (USPHS)UNKNOWN USPHS/IDSA Prevention of Opportunistic Infections Working Group
Dec 9, 2014·Human Vaccines & Immunotherapeutics·Kuan-Yeh LeeChien-Ching Hung
Apr 2, 2005·Clinics in Chest Medicine·Andrew F Shorr
Mar 7, 2001·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·R A SmegoK P Klugman
Aug 30, 2016·HIV Medicine·Anna Maria GerettiAlison Rodger
Feb 24, 2017·Expert Review of Respiratory Medicine·Charles FeldmanTheresa Rossouw
Mar 29, 2014·International Journal of STD & AIDS·Anne-Lise MunierJean-Michel Molina
Oct 14, 2014·Journal of the International AIDS Society·Jennifer A VeltmanJeffrey D Klausner
Oct 1, 2005·Expert Review of Pharmacoeconomics & Outcomes Research·Pedro Plans-Rubió

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