Risk factors for postoperative lower-extremity lymphedema in endometrial cancer survivors who had treatment including lymphadenectomy

Gynecologic Oncology
Yukiharu TodoHidenori Kato

Abstract

The aim of this study was to determine the incidence rate of lower-extremity lymphedema after systematic lymphadenectomy in patients with uterine corpus malignancies and to elucidate risk factors for this type of lymphedema. A retrospective chart review was carried out for all patients with uterine corpus malignant tumor managed at Hokkaido Cancer Center between 1991 and 2007. Patients who did not undergo lymphadenectomy as a treatment or died of cancer/intercurrent disease were excluded from this study. All living patients included in this study had hysterectomy, bilateral salpingo-oophorectomy and lymphadenectomy and their medical records were reviewed. We identified patients with postoperative lower-extremity lymphedema (POLEL). Logistic regression analysis was used to select the risk factors for POLEL. Of 286 patients evaluated, 103 (37.8%) had POLEL. Multivariate analysis confirmed that adjuvant radiation therapy (OR=5.2, 95% CI=2.1-12.7), resection of more than 31 lymph nodes (OR=2.6, 95% CI=1.4-4.9), and removal of circumflex iliac nodes to the distal external iliac nodes (CINDEIN) (OR=6.1, 95% CI=1.3-28.2) were independent risk factors for POLEL. Adjuvant radiation therapy should be avoided in patients who undergo syste...Continue Reading

References

Mar 2, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Janiel M CragunAndrew Berchuck
Apr 10, 2008·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Jürgen FüllerThomas G Wendt
Nov 27, 2008·Journal of the National Cancer Institute·Pierluigi Benedetti PaniciCostantino Mangioni

❮ Previous
Next ❯

Citations

Jun 7, 2014·Gynecologic Oncology·William M BurkeUNKNOWN Society of Gynecologic Oncology Clinical Practice Committee
Oct 29, 2013·Women's Health·Sarah HorvathThomas J Herzog
Sep 24, 2013·World Journal of Surgical Oncology·Pankaj TiwariStephen P Povoski
Feb 9, 2012·International Journal of Surgical Oncology·Nikki L Neubauer, John R Lurain
Jan 8, 2011·International Journal of Clinical Oncology·Yoko OhbaNoriaki Sakuragi
Feb 16, 2013·International Journal of Clinical Oncology·Mariam M AlHilli, Andrea Mariani
Mar 5, 2016·Gynecologic Oncology Reports·Elizabeth E HoppDenise S Uyar
Oct 1, 2013·Journal of Vascular Surgery. Venous and Lymphatic Disorders·Takumi YamamotoIsao Koshima
Apr 1, 2013·Journal of Vascular Surgery. Venous and Lymphatic Disorders·Makoto MiharaIsao Koshima
Nov 3, 2012·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·A AchouriF Lécuru
May 20, 2015·Annals of Surgical Oncology·Hyo Sook BaeSang-Yoon Park
Jan 3, 2013·The Journal of Obstetrics and Gynaecology Research·Yukiharu Todo, Noriaki Sakuragi
Jan 11, 2012·The Journal of Obstetrics and Gynaecology Research·Hidenori KatoNoriaki Sakuragi
Mar 24, 2016·International Journal of Surgery·Juan ZhouFeng-Yan Li
Jan 30, 2014·The Journal of Obstetrics and Gynaecology Research·Yukiharu TodoNoriaki Sakuragi
Mar 31, 2015·Best Practice & Research. Clinical Obstetrics & Gynaecology·Martin KoskasFrederic Amant
Jun 6, 2015·Best Practice & Research. Clinical Obstetrics & Gynaecology·S P Somashekhar
Nov 6, 2013·Obstetrics and Gynecology International·Fabien Vidal, Arash Rafii
Mar 19, 2014·Gynecologic Oncology·Ingrid J RowlandsUNKNOWN Australian National Endometrial Cancer Study Group
Feb 26, 2016·Gynecologic Oncology·Callie M Cox BauerScott A Kamelle
Aug 28, 2016·Surgical Oncology·Alberto A MendivilBram H Goldstein
Oct 25, 2016·Gynecologic Oncology·Abdulrahman K SinnoEdward J Tanner
Aug 31, 2013·Journal of the National Cancer Institute·Kathryn H SchmitzBettina F Drake
Sep 26, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Electra D PaskettJ Phil Harrop
Sep 21, 2017·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Chiaki OmichiHisashi Masuyama
Jul 9, 2014·Obstetrics and Gynecology·Kathleen J YostSean C Dowdy

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.