Risk Factors for Progression of Conservatively Managed Acute Traumatic Subdural Hematoma: A Systematic Review and Meta-Analysis.

World Neurosurgery
Vishwa Bharathi GaonkarShashank S Kale

Abstract

Conservatively managed posttraumatic acute subdural hematoma (SDH) can present with progression of the size of the hematoma with increased mass effect, necessitating delayed surgery. The factors contributing to this progression remain largely unknown. A comprehensive search of the PubMed, Embase, and Scopus databases was performed to retrieve case control studies, retrospective cohort studies, and prospective studies with retrospective evaluation of risk factors until August 2, 2020. The different risk factors that were evaluated in the studies were compiled and the results were analyzed to arrive at a conclusion. A total of 7 studies were included in the systematic review and 6 were included in the analysis, with an aggregate of 679 patients. The following factors were found to have a relation with progression of acute SDH: age (odds ratio, 7.12; 95% confidence interval [CI], 2.52-11.72), use of antiplatelet drugs (odds ratio, 1.89; 95% CI, 1.18-2.77), use of anticoagulants (odds ratio, 3.09; 95% CI, 1.21-7.88), thickness of SDH (odds ratio, 4.13; 95% CI, 3.29-4.97), midline shift (odds ratio, 1.86; 95% CI, 0.69-3.03), hypertension (odds ratio, 2.22; 95% CI, 1.25-3.96) and ischemic heart disease (odds ratio, 3.32; 95% CI, 1.63...Continue Reading

References

Sep 26, 2006·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Tilmann RustAlbert Erasmus
Feb 11, 2012·Journal of Korean Neurosurgical Society·Kyeong-Seok LeeHack-Gun Bae
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Jun 11, 2019·Journal of Neurological Surgery. Part A, Central European Neurosurgery·Stefanie KaestnerWolfgang Deinsberger

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Citations

Apr 1, 2021·Journal of Neurotrauma·Ellie EdlmannPeter J Hutchinson

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