Risk factors for recurrent ureteropelvic junction obstruction after open pyeloplasty in a large pediatric cohort

The Journal of Urology
Luis H P BragaJoao L Pippi Salle

Abstract

Recurrent ureteropelvic junction obstruction after open pyeloplasty is a serious complication for which treatment remains challenging. We identified risk factors for persistent obstruction. We retrospectively reviewed the charts of 401 children who underwent open dismembered pyeloplasty between 1997 and 2005. Of these children 21 (5.2%) experienced recurrent ureteropelvic junction obstruction. Age, prenatal diagnosis, hydronephrosis grade, differential renal function, incision location (flank or dorsal lumbotomy), retrograde pyelography and stent placement were analyzed. Univariate and multivariate analyses were performed to identify risk factors for pyeloplasty failure. Median age at surgery was 21 months and median followup was 36 months. Of the 401 patients dorsal lumbotomy was performed in 171 (42.6%) and a flank incision was used in 230 (57.4%). Retrograde pyelography was done in 195 patients (48.6%) and stents were used in 352 (87%). Age, prenatal diagnosis, degree of hydronephrosis, differential renal function and stent placement did not have an impact on pyeloplasty outcome on univariate analysis. Recurrent ureteropelvic junction obstruction developed in 14 of 171 patients who had originally undergone dorsal lumbotomy v...Continue Reading

References

Apr 1, 1992·Journal of Pediatric Surgery·C A SheldonH M Snyder
Aug 1, 1990·The Journal of Urology·S N Cockrell, W H Hendren
May 1, 1981·The Journal of Urology·L PerskyK Kedia
Aug 1, 1994·The Journal of Urology·H G RushtonM Majd
Dec 1, 1993·The Journal of Urology·F J Sampaio, L A Favorito
Aug 1, 1996·The Journal of Urology·D J Lim, R D Walker
Jan 1, 1996·European Urology·J BanielC Servadio
Sep 1, 1997·The Journal of Urology·D RohrmannS A Zderic
Jun 24, 1999·The Journal of Urology·B P DuelR González
Jan 13, 2000·Pediatric Surgery International·R Kumar, G Smith
Nov 11, 2005·The Journal of Urology·J C ThomasJ W Brock

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Citations

Feb 15, 2011·Cardiovascular and Interventional Radiology·Alex M BarnacleDerek J Roebuck
Apr 3, 2014·Journal of Pediatric Urology·Sarath Kumar NarayananRalph Clinton Cohen
Sep 17, 2013·Urology·Rodrigo L P RomaoWalid A Farhat
Jan 15, 2013·The Journal of Urology·Ahmed M HarrazAshraf T Hafez
Jun 20, 2012·Actas urologicas españolas·C E Lasso-BetancorR Gosalbez
Sep 22, 2009·The Journal of Urology·Marco Castagnetti
Mar 2, 2016·The Journal of Urology·Geolani W DyJonathan D Harper
Jul 6, 2015·Pediatric Surgery International·Vijaya M VemulakondaAllison Kempe
Apr 30, 2011·The Journal of Urology·Eduardo RuizFrancisco Ignacio de Badiola
Mar 13, 2020·International Journal of Urology : Official Journal of the Japanese Urological Association·Miyuki KohnoMasayuki Kubota
Nov 22, 2020·Journal of Pediatric Urology·Sanni VäreläMartin Salö
Dec 12, 2019·Urologia Internationalis·Asmaa IsmailAhmed Kotb

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