Risk factors for the development of delirium in alcohol dependence syndrome: Clinical and neurobiological implications

Indian Journal of Psychiatry
Sukanto SarkarJanet Konthoujam

Abstract

Alcohol withdrawal delirium (AWD) or delirium tremens (DT) is associated with severe complications and high mortality. Prospectively identifying patients with increased risk of developing DT would have important preventive and therapeutic implications. Thus, the present study aimed to identify clinical risk factors predicting the development of DT. The study was a cross-sectional quasi-experimental one with equivalent control group, conducted at a tertiary hospital from August 2014 to May 2015. Forty adult male inpatients, diagnosed with DT, were compared with forty age- and sex-matched inpatients in alcohol withdrawal state without delirium. Assessments were done using confusion assessment method, Clinical Institute Withdrawal Assessment of Alcohol Scale, and Mini-Mental Status Examination. For group comparisons, Pearson's Chi-square test and independent sample t-test were used; logistic regression was applied to identify predictors followed by receiver operating characteristic curve analysis. Heavy drinking (P = 0.005; odds ratio [OR]: 1.17, confidence interval [CI]: 1.05-1.31), continuous pattern of drinking (P = 0.027; OR: 4.67, CI: 1.19-18.33), past history of delirium (P = 0.009; OR: 552.8, CI: 4.88-625.7), alcohol-induce...Continue Reading

Citations

Dec 4, 2019·JBI Database of Systematic Reviews and Implementation Reports·Yimenu YitayihMatiwos Soboka
May 1, 2021·Journal of Neurosciences in Rural Practice·Sandeep GroverDevakshi Dua
Nov 22, 2020·La Revue de médecine interne·N ThiercelinJ Azuar

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Statistical Package for the Social Sciences ( SPSS

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