Risk factors for the development of retroprosthetic membranes with Boston keratoprosthesis type 1: multicenter study results.

Ophthalmology
Christopher J RudniskyBoston Type 1 Keratoprosthesis Study Group

Abstract

The purpose of this study was to identify possible risk factors for retroprosthetic membrane (RPM) development in a large, multicenter cohort of patients receiving a Boston type 1 keratoprosthesis. Cohort study. The final analysis included 265 eyes of 265 patients who underwent implantation of a Boston keratoprosthesis type I device between January 2003 and July 2008 by 1 of 19 surgeons at 18 medical centers. Forms reporting preoperative, intraoperative, and postoperative parameters were prospectively collected and subsequently analyzed at a central data collection site. The primary outcome was the presence or absence of an RPM during the follow-up period. The average age of patients was 63.3±19.1 years, 48.5% of the patients were female, and 52.5% of procedures were performed on the right eye. The mean follow-up time was 17.8±14.9 months. The majority (85.4%; n = 222) had undergone an average of 2.2±1.2 (range, 1-8) penetrating keratoplasties before keratoprosthesis implantation, and 38 eyes (14.6%) received a primary keratoprosthesis. The overall RPM formation rate was 31.7% (n = 84). The most significant risk factor for RPM development was infectious keratitis (as a surgical indication for keratoprosthesis surgery itself), r...Continue Reading

References

Apr 17, 1998·Ophthalmology·P A NetlandC H Dohlman
Feb 24, 2001·Cornea·F YaghoutiC H Dohlman
Jul 15, 2005·Cornea·Celia R Hicks, Stephen Hamilton
Dec 27, 2005·American Journal of Ophthalmology·James V AquavellaJayachandra Reddy Palakuru
Jul 29, 2006·Ophthalmology·Brian L ZerbeUNKNOWN Boston Type 1 Keratoprosthesis Study Group
Jan 22, 2008·American Journal of Ophthalmology·Rony R SayeghClaes H Dohlman
Aug 6, 2009·Cornea·Robert E FintelmannBrandon D Ayres
Sep 3, 2009·Cornea·Hall F ChewElisabeth J Cohen
Jul 9, 2010·International Ophthalmology Clinics·Michael A Klufas, Kathryn A Colby

❮ Previous
Next ❯

Citations

Aug 27, 2013·Cornea·Matthew T FengFrancis W Price
Oct 8, 2013·Cornea·Andrea CruzatKathryn Colby
Jan 7, 2014·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Maria Fideliz de la PazRalph Michael
Nov 1, 2013·Asia-Pacific Journal of Ophthalmology·Annabel C Y ChewDonald T H Tan
Sep 24, 2015·Retina·Pukhraj RishiBhaskar Srinivasan
Jun 19, 2013·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Angela Qiao ZhangAllan Slomovic
Nov 10, 2015·American Journal of Ophthalmology·Christopher J RudniskyUNKNOWN Boston Type 1 Keratoprosthesis Study Group
Mar 19, 2013·Ophthalmology·Joseph B CiolinoUNKNOWN Boston Keratoprosthesis Type 1 Study Group
Jan 29, 2013·American Journal of Ophthalmology·Kavitha R SivaramanM Soledad Cortina
Aug 15, 2015·The British Journal of Ophthalmology·Namrata SharmaRasik B Vajpayee
Jul 15, 2015·Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society·Khalid Al Arfaj
Apr 18, 2016·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Christopher W NoelAllan R Slomovic
Jun 27, 2015·Cornea·Mustafa KoskerKristin M Hammersmith
Oct 18, 2014·Seminars in Ophthalmology·Marie-Claude Robert, Claes H Dohlman
Oct 18, 2014·Seminars in Ophthalmology·Bobeck S Modjtahedi, Dean Eliott
Oct 29, 2014·The British Journal of Ophthalmology·Venkata S Avadhanam, Christopher S C Liu
May 23, 2014·American Journal of Ophthalmology·Salima I HassanalyMona Harissi-Dagher
Apr 22, 2015·Survey of Ophthalmology·Michael A KlufasSzilárd Kiss
Apr 15, 2016·Cornea·Borja Salvador-CullaMiguel A López
May 7, 2016·The Ocular Surface·Jayesh VaziraniVirender S Sangwan
Dec 13, 2016·Ocular Immunology and Inflammation·Ashik MohamedVirender S Sangwan
Mar 14, 2018·The International Journal of Artificial Organs·Heng Sun, Zhu-Lin Hu
Nov 6, 2014·The Cochrane Database of Systematic Reviews·Esen K AkpekKristina Lindsley
Aug 28, 2016·The British Journal of Ophthalmology·Petros PetrouDavid G Charteris
May 15, 2020·The Cochrane Database of Systematic Reviews·Masako ChenSumayya Ahmad
May 20, 2020·Clinical Ophthalmology·Manachai NonpassoponMaria Soledad Cortina
Dec 9, 2017·Eye & Contact Lens·Aaron R KaufmanKathryn A Colby
Dec 18, 2020·Cornea·Takashi OnoKazunori Miyata
Jun 28, 2019·American Journal of Ophthalmology·Rafaella Nascimento E SilvaMilton R Alves
Jun 9, 2021·American Journal of Ophthalmology·Pinnita PrabhasawatWarinyupa Pinitpuwadol

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.