Abstract
To evaluate the parameters which could predict the persistence of respiratory symptoms in asthmatic children who have been treated with a considerably uniform therapy. A retrospective review was performed on the records of 279 children with asthma. An end of study visit, results of spirometry and prick tests completed the data. The mean age at referral and at final visit was 6.2 +/- 3.7 years and 8.9 +/- 4.1 years, respectively; and the children were followed up for a mean of 3 +/- 1.2 years. Eighty-five of the 279 patients (30%) experienced no respiratory symptoms in the previous 12 months. There was no significant difference between those with and without current respiratory symptoms with respect to age, sex, age at onset of symptoms, duration of followup, age at referral, therapeutic choice, severity of asthma and duration of symptoms at referral. For subjects with current respiratory symptoms the initial serum total IgE level, and the percentage of RAST/prick test positivity was significantly higher than those without current respiratory symptoms (P = 0.0027, P = 0.011, respectively). Although the initial FEF 25%-75%, FEV1, and FEV1/FVC was significantly lower in those with current respiratory symptoms (P = 0.003; P = 0.005...Continue Reading
References
Sep 1, 1992·The American Review of Respiratory Disease·E E van Essen-ZandvlietK F Kerrebijn
Aug 8, 1991·The New England Journal of Medicine·T HaahtelaO Selroos
Nov 1, 1989·The American Review of Respiratory Disease·J GerritsenK Knol
Jul 1, 1988·The American Review of Respiratory Disease·W J KellyA Olinsky
Apr 25, 1987·British Medical Journal·W J KellyA Olinsky
Apr 1, 1987·The Journal of Allergy and Clinical Immunology·K F KerrebijnH J Neijens
Oct 1, 1986·Chest·S Bronnimann, B Burrows
Feb 1, 1968·American Journal of Diseases of Children·D E Johnstone
Sep 1, 1966·American Journal of Diseases of Children·W P Buffum, G A Settipane
May 1, 1994·Respiratory Medicine·L Agertoft, S Pedersen
Jul 9, 1994·BMJ : British Medical Journal·M A JenkinsG G Giles
Jan 1, 1994·American Journal of Respiratory and Critical Care Medicine·D J GoddenJ G Douglas
Dec 1, 1993·The American Review of Respiratory Disease·R J RoordaK Knol
Feb 1, 1993·The Nurse Practitioner·G RachelefskyB Santamaria
Jan 1, 1996·Thorax·R J Roorda
Dec 1, 1996·American Journal of Respiratory and Critical Care Medicine·D P StrachanH R Anderson
Dec 1, 1996·The Journal of Allergy and Clinical Immunology·P König, J Shaffer
Feb 25, 1998·Pediatric Pulmonology·J O Warner, C K Naspitz
Apr 1, 1998·American Journal of Respiratory and Critical Care Medicine·P J BarnesW W Busse
May 1, 1998·The Journal of Allergy and Clinical Immunology·N Barnes
Aug 12, 1998·American Journal of Respiratory and Critical Care Medicine·N J WithersJ B Clough
Citations
May 30, 2006·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Ignazio CirilloGiorgio Ciprandi
Aug 29, 2013·BioMed Research International·Aerik A WilliamsPatricia Padams
Nov 10, 2012·Allergologia et immunopathologia·Ö BağH T Nacaroğlu
Nov 3, 2010·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·K C Lødrup CarlsenK-H Carlsen
Jul 19, 2012·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·I ChinellatoG Piacentini
Aug 25, 2011·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Nadia N HanselGregory B Diette
Aug 8, 2013·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Metin AydoganIsil Barlan
Oct 12, 2010·Chest·Massimo PifferiAttilio L Boner
Dec 22, 2006·American Journal of Rhinology·Giorgio CiprandiMariangela Tosca
Jul 16, 2010·Pediatric Pulmonology·Rhonda J RosychukBrian H Rowe
Apr 18, 2009·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Imran KhalidZachary Q Morris