Risk factors for the persistence of respiratory symptoms in childhood asthma

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
N N BahçecilerM M Başaran

Abstract

To evaluate the parameters which could predict the persistence of respiratory symptoms in asthmatic children who have been treated with a considerably uniform therapy. A retrospective review was performed on the records of 279 children with asthma. An end of study visit, results of spirometry and prick tests completed the data. The mean age at referral and at final visit was 6.2 +/- 3.7 years and 8.9 +/- 4.1 years, respectively; and the children were followed up for a mean of 3 +/- 1.2 years. Eighty-five of the 279 patients (30%) experienced no respiratory symptoms in the previous 12 months. There was no significant difference between those with and without current respiratory symptoms with respect to age, sex, age at onset of symptoms, duration of followup, age at referral, therapeutic choice, severity of asthma and duration of symptoms at referral. For subjects with current respiratory symptoms the initial serum total IgE level, and the percentage of RAST/prick test positivity was significantly higher than those without current respiratory symptoms (P = 0.0027, P = 0.011, respectively). Although the initial FEF 25%-75%, FEV1, and FEV1/FVC was significantly lower in those with current respiratory symptoms (P = 0.003; P = 0.005...Continue Reading

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Citations

May 30, 2006·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Ignazio CirilloGiorgio Ciprandi
Aug 29, 2013·BioMed Research International·Aerik A WilliamsPatricia Padams
Nov 3, 2010·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·K C Lødrup CarlsenK-H Carlsen
Jul 19, 2012·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·I ChinellatoG Piacentini
Aug 25, 2011·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Nadia N HanselGregory B Diette
Aug 8, 2013·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Metin AydoganIsil Barlan
Dec 22, 2006·American Journal of Rhinology·Giorgio CiprandiMariangela Tosca
Apr 18, 2009·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Imran KhalidZachary Q Morris

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