Risk factors for treatment failure in renal suppurative infections.

International Urology and Nephrology
M StojadinovićSlobodan M Janković

Abstract

There are conflicting results of published studies about prognostic value of various factors in purulent renal infections. The purpose of this study was to identify and quantify potential risk factors for early and late treatment failure in such infections. A retrospective review of 75 renal suppurative infections, at three tertiary Serbian Clinics of Urology, was conducted. We considered numerous potential risk factors in a multivariate analysis. This series was comprised of 49 women and 26 men, with mean age of 56.7 years. There were 38 and 37 patients who experienced successful and unfavorable early treatment outcome, respectively. Overall mortality rate was 9.3%. Comorbidity [odds ratio (OR) = 1.6], complex suppurative pathological findings (OR = 3.6), presence of Pseudomonas spp. (OR = 6.7), multiple bacterial strains (OR = 2.7), and positive culture itself (OR = 3.6) were the predictors of poor early prognosis. A urological intervention and presence of pyonephrosis significantly increased the chance for good initial outcome (OR = 0.32 and 0.37, respectively). In the late treatment failure analysis presence of comorbidities (OR = 5.8) and treatment complications (OR = 7.5) significantly increased chance for fatal outcome. ...Continue Reading

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Citations

May 7, 2011·Surgical Infections·Miroslav M StojadinovićBranko S Gajić
Jun 4, 2011·Acta chirurgica Iugoslavica·Ljiljana Marković-DenićMilan Djokić
Jun 17, 2015·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Maria BitsoriEmmanouil Galanakis

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