Abstract
Longitudinal studies on bone mass decline for healthy women are sparse. We performed a retrospective longitudinal study to evaluate the factor associated with bone mass changes at the lumbar spine in healthy Korean pre- and perimenopausal women over the age of 40. We examined the relation of blood tests including thyroid function tests at baseline and follow-up to the annual percentage changes in average BMD of L2-L4 (A%ΔLSBMD). Four hundred and forty-three subjects without diseases or medications pertaining to bone metabolism were analyzed. The mean A%ΔLSBMD in these subjects was -0.45%/year. Though a significant correlation was observed between the A%ΔLSBMD and age, serum thyroid-stimulating hormone (TSH) level, total cholesterol (TC) level, low-density lipoprotein cholesterol (LDL-C) level, and estimated glomerular filtration rate (eGFR) at baseline and follow-up, there was a weak correlation between A%ΔLSBMD and these variables. From multiple linear regression analyses, the percent body fat, age, serum TSH level, serum uric acid level, and the menopause at follow-up were showed to have a significant association with the A%ΔLSBMD. Unlike age, percent body fat, and menopause at follow-up, which had a negative association with...Continue Reading
References
Nov 1, 1992·Clinical Endocrinology·J E CompstonK T Khaw
Sep 17, 1994·BMJ : British Medical Journal·G JonesJ A Eisman
May 1, 1993·Calcified Tissue International·J M PouillesC Ribot
May 18, 1996·BMJ : British Medical Journal·D MarshallH Wedel
Oct 1, 1996·Nature Medicine·D E HughesB F Boyce
Jun 24, 2000·JAMA : the Journal of the American Medical Association·P S WangJ Avorn
Jul 6, 2000·Lancet·K A ChanR Platt
Jun 1, 2001·The American Journal of Psychiatry·P S WangJ Avorn
Jun 7, 2002·Endocrine Reviews·B Lawrence RiggsL Joseph Melton
Jun 26, 2002·Endocrine Journal·Toru YamaguchiKazuo Chihara
Oct 22, 2003·Cell·Etsuko AbeMone Zaidi
Sep 17, 2005·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Lian-Hua CuiJin-Su Choi
Dec 27, 2005·Current Pharmaceutical Design·G K GlantzounisD A Galaris
Jan 10, 2006·The American Journal of Clinical Nutrition·Yi-Hsiang HsuXiping Xu
Jan 13, 2006·Clinical Endocrinology·Duk Jae KimGhi Su Kim
Apr 20, 2006·Journal of Women's Health·R A Brownbill, J Z Ilich
Sep 19, 2006·Metabolism: Clinical and Experimental·Sofia G TsouliMoses S Elisaf
Jan 24, 2007·Bone·Martha Savaria Morris
Apr 24, 2007·QJM : Monthly Journal of the Association of Physicians·E M DennisonUNKNOWN Hertfordshire Cohort Study Group
Sep 12, 2007·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M SugiuraM Yano
Dec 28, 2007·The Journal of Clinical Endocrinology and Metabolism·Joel S FinkelsteinRobert M Neer
Jul 18, 2008·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·S MorinW D Leslie
Oct 18, 2008·Thyroid : Official Journal of the American Thyroid Association·Guri GrimnesRolf Jorde
May 26, 2009·Joint, Bone, Spine : Revue Du Rhumatisme·Omer Faruk SendurMukadder Serter
Oct 27, 2010·Calcified Tissue International·In-Kyong JeongChan Soo Shin
Jan 14, 2011·Endocrine Research·Jiunn-Diann LinSai-Hung Tang
Mar 5, 2011·Current Osteoporosis Reports·Yahtyng Sheu, Jane A Cauley
May 5, 2011·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Iraj NabipourMarkus J Seibel
Oct 19, 2011·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·J H KimN H Cho
Jun 16, 2012·The Journal of Clinical Endocrinology and Metabolism·Eun Young LeeSung-Kil Lim
Nov 1, 2012·Bone·Joanna MakoveyPhilip N Sambrook
Citations
Jul 17, 2012·Taiwanese Journal of Obstetrics & Gynecology·Tzay-Shing YangKo-En Huang
Oct 12, 2016·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M PirroT Merriman
Feb 11, 2016·Endocrine Reviews·J H Duncan Bassett, Graham R Williams
Apr 24, 2018·Endocrine Reviews·Gherardo MazziottiAndrea Giustina
Nov 6, 2018·Endocrine, Metabolic & Immune Disorders Drug Targets·Neelam KaushalSujeet Jha
Feb 6, 2020·Experimental and Therapeutic Medicine·Sheng-Kai YeHai-Ying Chen
Aug 11, 2016·Hormone Molecular Biology and Clinical Investigation·Mone ZaidiTony Yuen
May 21, 2017·Archives of Osteoporosis·Wen HanXiangmei Chen
Dec 19, 2019·International Journal of Molecular Sciences·Gloria BonaccorsiCarlo Cervellati
Aug 4, 2021·Menopause : the Journal of the North American Menopause Society·Wen HanXiangmei Chen