Risk factors of childhood epilepsy in Kerala.

Annals of Indian Academy of Neurology
Thomas Varghese AttumalilP A Mohammed Kunju

Abstract

We aimed to identify the risk factors for epilepsy in children. This case-control retrospective study was carried out in the pediatric neurology outpatient service of the Trivandrum Medical College. All children (1-12 years) with epilepsy satisfying the selection criteria were included, after obtaining consent from parents. Those with single seizures or febrile seizures were excluded. Controls were children without epilepsy attending the same hospital. Parents were interviewed and clinical data were obtained from medical records. Statistical analysis included chi-square test, odds ratio (OR), and logistic regression. There were 82 cases and 160 controls whose mean age was 6.9 + 3.6 and 5.2 + 3.1, years respectively. On univariate analysis, family history of epilepsy, prolonged labor, cyanosis at birth, delayed cry after birth, admission to newborn intensive care unit, presence of congenital malformations, neurocutaneous markers, incessant cry in the first week, delayed developmental milestones, meningitis, encephalitis, and head trauma were found to be significant. On logistic regression, family history of epilepsy (OR 4.7), newborn distress (OR 8.6), delayed developmental milestones (OR 12.6), and head trauma (OR 5.8) were fou...Continue Reading

Citations

Nov 13, 2015·Epilepsy & Behavior : E&B·Alexandra VollJose F Téllez-Zenteno
Oct 2, 2015·Annals of Indian Academy of Neurology·Senthil AmudhanParthasarathy Satishchandra
Nov 29, 2020·Epilepsy & Behavior : E&B·Aya Al HabbalAmeer Kakaje

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